The association between CPR quality of In-hospital resuscitation and sex: A hypothesis generating, prospective observational study.
AHA, American Heart Association
CI, confidence interval
CPC, Cerebral Performance Category
CPM, Compressions per minute
CPR, Cardiopulmonary resuscitation
Cardiopulmonary resuscitation
DNAR, Do not attempt resuscitation
EMR, Electronic medical record
Heart arrest
IHCA, In-hospital cardiac arrest
IHD, Ischemic heart disease
IRB, Institutional review board
Mortality
NFF, No-flow-fraction
NFT, No-flow-time
OHCA, Out-of-hospital cardiac arrest
OR, Odds ratio
ROSC, Return of spontaneous circulation
Return of spontaneous circulation
Sex characteristics
Journal
Resuscitation plus
ISSN: 2666-5204
Titre abrégé: Resusc Plus
Pays: Netherlands
ID NLM: 101774410
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
27
03
2022
revised:
12
07
2022
accepted:
12
07
2022
entrez:
8
8
2022
pubmed:
9
8
2022
medline:
9
8
2022
Statut:
epublish
Résumé
The relationship between sex and cardiopulmonary resuscitation (CPR) outcomes remains unclear. Particularly, questions remain regarding the potential contribution of unmeasured confounders. We aimed to examine the differences in the quality of chest compression delivered to men and women. Prospective study of observational data recorded during consecutive resuscitations occurring in a single tertiary center (Feb-1-2015 to Dec-31-2018) with real-time follow-up to hospital discharge. The studied variables included time in CPR, no-flow-time and fraction, compression rate and depth and release velocity. The primary study endpoint was the unadjusted association between patient sex and the chest compression quality (depth and rate). The secondary endpoint was the association between the various components of chest compression quality, sex, and survival to hospital discharge/neurologically intact survival. Overall 260 in-hospital resuscitations (57.7% male patients) were included. Among these 100 (38.5%) achieved return of spontaneous circulation (ROSC) and 35 (13.5%) survived to hospital discharge. Female patients were significantly older. Ischemic heart disease and ventricular arrhythmias were more prevalent among males. Compression depth was greater in female vs male patients (54.9 ± 11.3 vs 51.7 ± 10.9 mm; Women received deeper chest compressions during in-hospital CPR. Our findings require corroboration in larger cohorts but nonetheless underscore the need to maintain high-quality CPR in all patients using real-time feedback devices. Future studies should also include data on ventilation rates and volumes which may contribute to survival outcomes.
Identifiants
pubmed: 35935175
doi: 10.1016/j.resplu.2022.100280
pii: S2666-5204(22)00080-7
pmc: PMC9352447
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100280Informations de copyright
© 2022 The Authors. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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