Synthesis and Biological Evaluation of Arylamide Sulphonate Derivatives as Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 and -3 Inhibitors.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
02 Aug 2022
02 Aug 2022
Historique:
received:
03
06
2022
accepted:
04
07
2022
entrez:
8
8
2022
pubmed:
9
8
2022
medline:
9
8
2022
Statut:
epublish
Résumé
Aberrant level of ectonucleotide pyrophosphatase/phosphodiesterase-1 and -3 is linked with numerous disorders, for instance, diabetes, cancer, osteoarthritis, chondrocalcinosis, and allergic reactions. These disorders may be cured or minimized by blocking the activity of ENPP1 and ENPP3 isozymes. In this study, arylamide sulphonates were synthesized, characterized, and evaluated for their capability to affect the activity of isozymes ENPP1 and ENPP3. Among the selective inhibitors of ENPP1, compounds
Identifiants
pubmed: 35936461
doi: 10.1021/acsomega.2c03473
pmc: PMC9352230
doi:
Types de publication
Journal Article
Langues
eng
Pagination
26905-26918Informations de copyright
© 2022 The Authors. Published by American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
Références
Biochim Biophys Acta. 2008 Sep;1781(9):513-8
pubmed: 18621144
Biochem J. 2004 Jul 1;381(Pt 1):71-7
pubmed: 15096095
Int Arch Allergy Immunol. 2004 Apr;133(4):317-29
pubmed: 15031605
J Biol Chem. 2007 May 25;282(21):15872-83
pubmed: 17383965
Hepatology. 1997 Apr;25(4):995-1002
pubmed: 9096610
Semin Cell Dev Biol. 2004 Oct;15(5):477-89
pubmed: 15271293
Eur J Med Chem. 2021 May 5;217:113339
pubmed: 33744686
J Med Chem. 2007 Nov 29;50(24):6059-66
pubmed: 17973361
J Exp Med. 1970 Jun 1;131(6):1325-41
pubmed: 5419273
Bioorg Med Chem. 2019 Jul 1;27(13):2741-2752
pubmed: 31088715
Am J Physiol Heart Circ Physiol. 2011 Jul;301(1):H61-8
pubmed: 21490328
Osteoarthritis Cartilage. 2010 Nov;18(11):1496-501
pubmed: 20709180
Bioorg Chem. 2020 Nov;104:104305
pubmed: 33017718
FEBS J. 2018 Jul;285(13):2481-2494
pubmed: 29717535
Purinergic Signal. 2012 Sep;8(3):437-502
pubmed: 22555564
Eur J Med Chem. 2018 Jul 15;155:364-380
pubmed: 29902722
Anal Biochem. 1976 May 7;72:248-54
pubmed: 942051
J Biol Chem. 2005 Jun 17;280(24):23084-93
pubmed: 15788404
Curr Cancer Drug Targets. 2002 Mar;2(1):55-75
pubmed: 12188921
Purinergic Signal. 2006 Jun;2(2):361-70
pubmed: 18404476
Electrophoresis. 2008 Sep;29(17):3685-93
pubmed: 18803183
Eur J Biochem. 1994 Dec 1;226(2):433-43
pubmed: 8001561
Bioorg Chem. 2014 Dec;57:132-141
pubmed: 25462989
J Am Chem Soc. 2011 Aug 10;133(31):12021-30
pubmed: 21721554
Acta Crystallogr D Struct Biol. 2020 Sep 1;76(Pt 9):889-898
pubmed: 32876064
J Biol Chem. 2001 Jan 12;276(2):1361-8
pubmed: 11027689
Antimicrob Agents Chemother. 2014 May;58(5):2968-71
pubmed: 24566180
J Med Chem. 2014 Jun 12;57(11):4677-91
pubmed: 24846781
Purinergic Signal. 2005 Jun;1(2):193-204
pubmed: 18404504
Bioorg Med Chem Lett. 2016 Dec 15;26(24):5960-5966
pubmed: 27839684
Genomics. 1997 Oct 15;45(2):412-5
pubmed: 9344668
J Med Chem. 2010 Dec 23;53(24):8485-97
pubmed: 21090681
Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16876-81
pubmed: 23027977
Biochemistry. 2006 Aug 15;45(32):9788-803
pubmed: 16893180
Nat Struct Mol Biol. 2011 Feb;18(2):198-204
pubmed: 21240271
Biochim Biophys Acta. 2006 Mar;1761(3):281-91
pubmed: 16631405
Bioorg Chem. 2021 Feb;107:104538
pubmed: 33349456
Bioorg Chem. 2019 Feb;82:246-252
pubmed: 30391855
Eur J Med Chem. 2019 Nov 1;181:111560
pubmed: 31382118