Reduced Metabotropic Glutamate Receptor Type 5 Availability in the Epileptogenic Hippocampus: An

[3H]ABP688 autoradiography hippocampus mGluR5 temporal lobe epilepsy

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2022
Historique:
received: 02 03 2022
accepted: 02 06 2022
entrez: 8 8 2022
pubmed: 9 8 2022
medline: 9 8 2022
Statut: epublish

Résumé

Abnormalities in the expression of metabotropic glutamate receptor type 5 (mGluR5) have been observed in the hippocampus of patients with drug-resistant mesial Temporal Lobe Epilepsy (mTLE).

Identifiants

pubmed: 35937057
doi: 10.3389/fneur.2022.888479
pmc: PMC9355376
doi:

Types de publication

Journal Article

Langues

eng

Pagination

888479

Informations de copyright

Copyright © 2022 Zimmermann, Minuzzi, Aliaga Aliaga, Guiot, Hall, Soucy, Massarweh, El Mestikawy, Rosa-Neto and Kobayashi.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Schizophr Res. 2014 Sep;158(1-3):270-1
pubmed: 25043265
Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16342-7
pubmed: 22988116
Nat Commun. 2016 Feb 03;7:10604
pubmed: 26837579
Neurochem Res. 2014 Oct;39(10):1862-75
pubmed: 24493625
J Neurophysiol. 2002 Mar;87(3):1395-403
pubmed: 11877514
J Cereb Blood Flow Metab. 2015 Jul;35(7):1169-74
pubmed: 25806702
J Biol Chem. 2009 Dec 18;284(51):35827-38
pubmed: 19840937
Brain. 2006 Jan;129(Pt 1):96-107
pubmed: 16311265
Neurosciences (Riyadh). 2011 Jan;16(1):3-9
pubmed: 21206438
Neurology. 2008 Mar 18;70(12):964-8
pubmed: 18347319
Biochim Biophys Acta. 2012 Apr;1818(4):974-83
pubmed: 22155642
Methods Cell Biol. 2013;113:81-105
pubmed: 23317899
J Biol Chem. 2012 Feb 17;287(8):5412-25
pubmed: 22179607
J Neurosci. 2007 Jul 18;27(29):7696-704
pubmed: 17634364
Nature. 2014 Jul 31;511(7511):557-62
pubmed: 25042998
Neuroscientist. 2001 Aug;7(4):340-52
pubmed: 11488399
Cold Spring Harb Perspect Med. 2015 Jun 01;5(6):
pubmed: 26033084
Biol Psychiatry. 2007 Oct 1;62(7):747-55
pubmed: 17531207
J Nucl Med. 2006 Apr;47(4):698-705
pubmed: 16595505
Brain Res Mol Brain Res. 1996 Dec 31;43(1-2):105-16
pubmed: 9037524
Curr Opin Pharmacol. 2015 Feb;20:95-101
pubmed: 25529199
Bioorg Med Chem. 2007 Jan 15;15(2):903-14
pubmed: 17110115
Nat Neurosci. 2015 Mar;18(3):367-72
pubmed: 25710839
J Nucl Med. 2007 Jul;48(7):1207-15
pubmed: 17574984
Cereb Cortex. 2016 Oct 17;26(11):4170-4179
pubmed: 27578494
PLoS One. 2014 Mar 24;9(3):e92765
pubmed: 24663806
Front Neuroanat. 2015 Mar 05;9:23
pubmed: 25798091
Annu Rev Pharmacol Toxicol. 2010;50:295-322
pubmed: 20055706
Hippocampus. 2013 Dec;23(12):1212-30
pubmed: 23804486
J Neurocytol. 2001 May;30(5):403-11
pubmed: 11951051
Front Pharmacol. 2012 Nov 01;3:189
pubmed: 23125836
J Neurophysiol. 2002 Jan;87(1):621-5
pubmed: 11784776
Epilepsy Curr. 2005 May-Jun;5(3):107-12
pubmed: 16145617
Brain Res Brain Res Rev. 1999 Jan;29(1):83-120
pubmed: 9974152
Epilepsy Res. 2012 Sep;101(3):253-60
pubmed: 22591751
J Biol Chem. 2000 Oct 27;275(43):33750-8
pubmed: 10934211
Ann Neurol. 2019 Feb;85(2):218-228
pubmed: 30597619
J Neurosci. 2014 Mar 26;34(13):4589-98
pubmed: 24672004

Auteurs

Maria Zimmermann (M)

Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.
Translational Neuroimaging Laboratory, Douglas Research Institute, McGill University, Montréal, QC, Canada.

Luciano Minuzzi (L)

Translational Neuroimaging Laboratory, Douglas Research Institute, McGill University, Montréal, QC, Canada.
Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.

Arturo Aliaga Aliaga (A)

Translational Neuroimaging Laboratory, Douglas Research Institute, McGill University, Montréal, QC, Canada.
PET Unit, McConnell Brain Imaging Centre, Montréal, QC, Canada.

Marie-Christine Guiot (MC)

Department of Pathology, Montréal Neurological Institute, Montréal, QC, Canada.

Jeffery A Hall (JA)

Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.

Jean-Paul Soucy (JP)

Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.
PET Unit, McConnell Brain Imaging Centre, Montréal, QC, Canada.

Gassan Massarweh (G)

PET Unit, McConnell Brain Imaging Centre, Montréal, QC, Canada.

Salah El Mestikawy (S)

Department of Psychiatry, Douglas Research Institute, McGill University, Montréal, QC, Canada.

Pedro Rosa-Neto (P)

Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.
Translational Neuroimaging Laboratory, Douglas Research Institute, McGill University, Montréal, QC, Canada.

Eliane Kobayashi (E)

Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.

Classifications MeSH