Bovine Tuberculosis Epidemiology in Cameroon, Central Africa, Based on the Interferon-Gamma Assay.

Cameroon Mycobacterium bovis bovine tuberculosis cattle epidemiology interferon-gamma assay

Journal

Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658

Informations de publication

Date de publication:
2022
Historique:
received: 16 02 2022
accepted: 21 06 2022
entrez: 8 8 2022
pubmed: 9 8 2022
medline: 9 8 2022
Statut: epublish

Résumé

Despite sub-Saharan Africa (SSA) accounting for ~20% of the global cattle population, prevalence estimates and related risk factors of bovine tuberculosis (bTB) are still poorly described. The increased sensitivity of the IFN-γ assay and its practical benefits suggest the test could be useful to investigate bTB epidemiology in SSA. This study used a population-based sample to estimate bTB prevalence, identify risk factors and estimate the effective reproductive rate in Cameroonian cattle populations. A cross-sectional study was conducted in the North West Region (NWR) and the Vina Division (VIN) of Cameroon in 2013. A regional stratified sampling frame of pastoral cattle herds produced a sample of 1,448 cattle from 100 herds. In addition, a smaller cross-sectional study sampled 60 dairy cattle from 46 small-holder co-operative dairy farmers in the NWR. Collected blood samples were stimulated with bovine and avian purified protein derivatives, with extracted plasma screened using the IFN-γ enzyme-linked immunosorbent assay (Prionics Bovigam

Identifiants

pubmed: 35937301
doi: 10.3389/fvets.2022.877541
pmc: PMC9353046
doi:

Types de publication

Journal Article

Langues

eng

Pagination

877541

Informations de copyright

Copyright © 2022 Kelly, Gonzaléz Gordon, Egbe, Freeman, Mazeri, Ngwa, Tanya, Sander, Ndip, Muwonge, Morgan, Handel and Bronsvoort.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Robert F Kelly (RF)

Farm Animal Services, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Epidemiology, Economics and Risk Assessment (EERA) Group, The Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

Lina Gonzaléz Gordon (L)

Epidemiology, Economics and Risk Assessment (EERA) Group, The Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

Nkongho F Egbe (NF)

School of Life Sciences, University of Lincoln, Lincoln, United Kingdom.

Emily J Freeman (EJ)

Farm Animal Services, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

Stella Mazeri (S)

Epidemiology, Economics and Risk Assessment (EERA) Group, The Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

Victor N Ngwa (VN)

School of Veterinary Medicine and Sciences, University of Ngaoundere, Ngaoundere, Cameroon.

Vincent Tanya (V)

Cameroon Academy of Sciences, Yaoundé, Cameroon.

Melissa Sander (M)

Tuberculosis Reference Laboratory Bamenda, Hospital Roundabout, Bamenda, Cameroon.

Lucy Ndip (L)

Laboratory of Emerging Infectious Diseases, University of Buea, Buea, Cameroon.

Adrian Muwonge (A)

Epidemiology, Economics and Risk Assessment (EERA) Group, The Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

Kenton L Morgan (KL)

Institute of Ageing and Chronic Disease and School of Veterinary Science, University of Liverpool, Liverpool, United Kingdom.

Ian G Handel (IG)

Epidemiology, Economics and Risk Assessment (EERA) Group, The Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

Barend M D C Bronsvoort (BMDC)

Epidemiology, Economics and Risk Assessment (EERA) Group, The Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

Classifications MeSH