Specific Challenges in Geriatric Cirrhosis and Hepatic Encephalopathy.
Alcohol
Dementia
EncephalApp
Lewy Body Dementia
Parkinson’s disease
Progressive Supranuclear Palsy
Wernicke’s Encephalopathy
Journal
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
ISSN: 1542-7714
Titre abrégé: Clin Gastroenterol Hepatol
Pays: United States
ID NLM: 101160775
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
received:
24
02
2022
revised:
14
04
2022
accepted:
20
04
2022
entrez:
8
8
2022
pubmed:
9
8
2022
medline:
11
8
2022
Statut:
ppublish
Résumé
As the world's population ages, diseases predominantly found in the elderly now overlap with diseases that were thought to be the purview of younger patients. This includes chronic liver disease, which affects more than 2 billion people worldwide. Owing to the obesity epidemic (and associated metabolic diseases), nonalcoholic fatty liver disease has become the most common cause of chronic liver disease and cirrhosis. A major complication of cirrhosis is hepatic encephalopathy (HE), which becomes challenging to diagnose in elderly patients. HE is usually included in the differential diagnosis of acute delirium but not of reversible dementias. To illustrate this point, we present 2 cases of older patients that were misdiagnosed as having dementia and Parkinson's disease or a parkinsonian syndrome but had contributions from cirrhosis. Both cognitive impairment and tremor resolved with treatment of HE.
Identifiants
pubmed: 35940730
pii: S1542-3565(22)00463-3
doi: 10.1016/j.cgh.2022.04.035
pmc: PMC9373233
mid: NIHMS1807656
pii:
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
S20-S29Subventions
Organisme : CSRD VA
ID : I01 CX001076
Pays : United States
Organisme : AHRQ HHS
ID : R21 HS024004
Pays : United States
Organisme : NCATS NIH HHS
ID : R21 TR003095
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK130134
Pays : United States
Informations de copyright
Copyright © 2022 AGA Institute. Published by Elsevier Inc. All rights reserved.
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