Salivary film thickness and MUC5B levels at various intra-oral surfaces.
MUC5B level
Palatal surface area
Salivary film thickness
Salivary secretions
Sialopapers
Journal
Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
received:
07
05
2022
accepted:
13
07
2022
pubmed:
9
8
2022
medline:
3
2
2023
entrez:
8
8
2022
Statut:
ppublish
Résumé
In this study, we investigated the salivary film thickness and the MUC5B levels at various intra-oral locations in healthy volunteers, with a focus on the palate. Besides, measurements of the palatal surface area were included to explore the possible relationships between the palatal surface area and the palatal salivary film and MUC5B levels. The salivary film thickness was determined using filter strips, which were pressed to the mucosal surfaces of five different intra-oral locations; conductance was then analysed using a Periotron. After elution of the strips, the MUC5B levels at various intra-oral locations were determined using ELISA. The palatal surface area was measured using an intra-oral scanner. The surface area was subsequently calculated using the software. The anterior tongue had the thickest salivary film and also the highest levels of MUC5B, while the anterior palate had the thinnest salivary film and lowest MUC5B levels. There was no association between the palatal surface area and the salivary film thickness of the palate. The salivary film and MUC5B levels are unequally distributed over the intra-oral regions of the soft tissues. The lack of association between the palatal surface area and the salivary film thickness indicates that a larger surface area is not associated with a relative thinner palatal salivary film. The results of the current study increase our understanding of saliva distribution in the oral cavity and could be used as reference values for future studies.
Identifiants
pubmed: 35941397
doi: 10.1007/s00784-022-04626-3
pii: 10.1007/s00784-022-04626-3
pmc: PMC9889518
doi:
Substances chimiques
Mucin-5B
0
MUC5B protein, human
0
Types de publication
Journal Article
Langues
eng
Pagination
859-869Subventions
Organisme : Nederlands Tijdschrift voor Tandheelkunde (NTVT)
ID : OZB2018.01
Informations de copyright
© 2022. The Author(s).
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