Impact of sleeve gastrectomy on renal function in patients with morbid obesity: a 1-year prospective cohort study.


Journal

Langenbeck's archives of surgery
ISSN: 1435-2451
Titre abrégé: Langenbecks Arch Surg
Pays: Germany
ID NLM: 9808285

Informations de publication

Date de publication:
Dec 2022
Historique:
received: 26 11 2021
accepted: 01 08 2022
pubmed: 10 8 2022
medline: 25 2 2023
entrez: 9 8 2022
Statut: ppublish

Résumé

Obesity is an independent risk factor for renal injury. A more favorable metabolic environment following weight loss may theoretically lead to improved renal function. We aimed to evaluate the evolution of renal function one year after sleeve gastrectomy in a large prospective cohort of patients with morbid obesity and assess the influence of fat-free mass (FFM) changes. We prospectively included obese patients admitted for sleeve gastrectomy between February 2014 and November 2016. We also included a historical observational cohort of patients undergoing sleeve gastrectomy between January 2013 and January 2014 who had FFM evaluation. Patients were systematically evaluated 1 year after surgery. The estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. The FFM was estimated by analyzing computerized tomography (CT) scan sections from CT systematically performed 2 days and 1 year after sleeve gastrectomy to detect surgery complications. Five hundred sixty-three patients fulfilled the inclusion criteria. The mean age was 41.2 ± 0.5 years. The mean body mass index was 43.5 ± 0.3 kg/m Renal function assessed by eGFR is significantly improved at 1-year post-sleeve gastrectomy, independent of changes in skeletal muscle mass.

Identifiants

pubmed: 35943574
doi: 10.1007/s00423-022-02647-w
pii: 10.1007/s00423-022-02647-w
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3323-3332

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Delphine Sanchez (D)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.

Amandine Lebrun (A)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.
INSERM U996, FHU Hepatinov, Labex LERMIT, Clamart, France.

Sosthene Somda (S)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.
Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

Panagiotis Lainas (P)

Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Service de Chirurgie Digestive Minimale Invasive, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.

Karima Lamouri (K)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.

Sophie Prevot (S)

INSERM U996, FHU Hepatinov, Labex LERMIT, Clamart, France.
Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Service d'Anatomie Pathologique, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.

Micheline Njike-Nakseu (M)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.

Hadrien Tranchart (H)

Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Service de Chirurgie Digestive Minimale Invasive, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.

Martin Gaillard (M)

Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Service de Chirurgie Digestive Minimale Invasive, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.

Mohamad Zaidan (M)

Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Service Néphrologie-Dialyse-Transplantation, Hôpital Bicêtre, AP-HP Université Paris-Saclay, Le Kremlin-Bicêtre, France.

Axel Balian (A)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.
INSERM U996, FHU Hepatinov, Labex LERMIT, Clamart, France.

Ibrahim Dagher (I)

Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Service de Chirurgie Digestive Minimale Invasive, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.

Sylvie Naveau (S)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.
INSERM U996, FHU Hepatinov, Labex LERMIT, Clamart, France.
Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

Gabriel Perlemuter (G)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France.
INSERM U996, FHU Hepatinov, Labex LERMIT, Clamart, France.
Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

Cosmin Sebastian Voican (CS)

Service d'Hépato-Gastroentérologie Et Nutrition, Hôpital Antoine-Béclère, AP-HP Université Paris-Saclay, Clamart, France. cosmin.voican@aphp.fr.
INSERM U996, FHU Hepatinov, Labex LERMIT, Clamart, France. cosmin.voican@aphp.fr.
Faculté de Médecine Paris-Saclay, Université Paris-Saclay, Le Kremlin-Bicêtre, France. cosmin.voican@aphp.fr.

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