Appropriateness of Surgical Aortic Valve Replacement for Severe Aortic Stenosis Is Increasing.


Journal

The Annals of thoracic surgery
ISSN: 1552-6259
Titre abrégé: Ann Thorac Surg
Pays: Netherlands
ID NLM: 15030100R

Informations de publication

Date de publication:
07 Aug 2022
Historique:
received: 16 02 2022
revised: 23 05 2022
accepted: 16 07 2022
pubmed: 11 8 2022
medline: 11 8 2022
entrez: 10 8 2022
Statut: aheadofprint

Résumé

The adoption of transcatheter aortic valve replacement led to the development of appropriate use criteria (AUC) for transcatheter and surgical aortic valve replacement (SAVR) for aortic stenosis in 2017. This study hypothesized that appropriateness of SAVR improved after publication of AUC. All patients undergoing isolated SAVR for severe aortic stenosis in a regional cardiac surgical quality collaborative were evaluated using data from the Society of Thoracic Surgeons Adult Cardiac Surgery Database (2011-2021). After excluding endocarditis and emergency cases, appropriateness of SAVR (rarely appropriate, may be appropriate, or appropriate) was assigned to patients by using established criteria. The relationship of appropriateness with publication of AUC was assessed, as was variation in appropriateness over time and by center. Of 3035 patients across 17 centers, 106 (3.5%) underwent SAVR for an indication identified as rarely appropriate or may be appropriate. Patients who underwent SAVR for rarely or may be appropriate indications were significantly more likely to experience operative mortality (5.7% vs 1.6%, P = .001) as well as major morbidity (21.7% vs 10.5%, P < .001). Performance of rarely or may be appropriate SAVR significantly decreased over time (slope -0.51%/year, P trend < .001), and it was decreased after the release of the AUC (before release, 3.83% vs after release, 2.06%; P = .036). Substantial interhospital variation in appropriateness was observed (range of may be or rarely appropriate SAVR, 0%-10%). The majority of isolated SAVR for aortic stenosis was appropriate according to the 2017 AUC. Appropriateness improved after publication of AUC, and this improvement was associated with a significant reduction of major morbidity and mortality.

Sections du résumé

BACKGROUND BACKGROUND
The adoption of transcatheter aortic valve replacement led to the development of appropriate use criteria (AUC) for transcatheter and surgical aortic valve replacement (SAVR) for aortic stenosis in 2017. This study hypothesized that appropriateness of SAVR improved after publication of AUC.
METHODS METHODS
All patients undergoing isolated SAVR for severe aortic stenosis in a regional cardiac surgical quality collaborative were evaluated using data from the Society of Thoracic Surgeons Adult Cardiac Surgery Database (2011-2021). After excluding endocarditis and emergency cases, appropriateness of SAVR (rarely appropriate, may be appropriate, or appropriate) was assigned to patients by using established criteria. The relationship of appropriateness with publication of AUC was assessed, as was variation in appropriateness over time and by center.
RESULTS RESULTS
Of 3035 patients across 17 centers, 106 (3.5%) underwent SAVR for an indication identified as rarely appropriate or may be appropriate. Patients who underwent SAVR for rarely or may be appropriate indications were significantly more likely to experience operative mortality (5.7% vs 1.6%, P = .001) as well as major morbidity (21.7% vs 10.5%, P < .001). Performance of rarely or may be appropriate SAVR significantly decreased over time (slope -0.51%/year, P trend < .001), and it was decreased after the release of the AUC (before release, 3.83% vs after release, 2.06%; P = .036). Substantial interhospital variation in appropriateness was observed (range of may be or rarely appropriate SAVR, 0%-10%).
CONCLUSIONS CONCLUSIONS
The majority of isolated SAVR for aortic stenosis was appropriate according to the 2017 AUC. Appropriateness improved after publication of AUC, and this improvement was associated with a significant reduction of major morbidity and mortality.

Identifiants

pubmed: 35948120
pii: S0003-4975(22)01079-7
doi: 10.1016/j.athoracsur.2022.07.036
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Raymond J Strobel (RJ)

Division of Cardiac Surgery, University of Virginia, Charlottesville, Virginia.

Zeyad T Sahli (ZT)

Division of Cardiac Surgery, University of Virginia, Charlottesville, Virginia.

J Hunter Mehaffey (JH)

Division of Cardiac Surgery, University of Virginia, Charlottesville, Virginia.

Robert B Hawkins (RB)

Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.

Andrew M Young (AM)

Division of Cardiac Surgery, University of Virginia, Charlottesville, Virginia.

Mohammed Quader (M)

Division of Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, Virginia.

Gregory J Dehmer (GJ)

Department of Medicine, Carilion Clinic/Virginia Tech Carilion School of Medicine, Roanoke, Virginia.

Nicholas R Teman (NR)

Division of Cardiac Surgery, University of Virginia, Charlottesville, Virginia.

Leora T Yarboro (LT)

Division of Cardiac Surgery, University of Virginia, Charlottesville, Virginia.

Donald S Likosky (DS)

Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.

Vinay Badhwar (V)

Department of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown, West Virginia.

Irving L Kron (IL)

Division of Cardiac Surgery, University of Virginia, Charlottesville, Virginia.

Gorav Ailawadi (G)

Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan. Electronic address: ailawadi@umich.edu.

Classifications MeSH