Environmental influences on child health outcomes: cohorts of individuals born very preterm.
Journal
Pediatric research
ISSN: 1530-0447
Titre abrégé: Pediatr Res
Pays: United States
ID NLM: 0100714
Informations de publication
Date de publication:
04 2023
04 2023
Historique:
received:
14
01
2022
accepted:
19
07
2022
revised:
27
05
2022
medline:
28
4
2023
pubmed:
11
8
2022
entrez:
10
8
2022
Statut:
ppublish
Résumé
The National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) Program was designed to address solution-oriented research questions about the links between children's early life environment and their risks of pre-, peri-, and post-natal complications, asthma, obesity, neurodevelopmental disorders, and positive health. Children born very preterm are at increased risk for many of the outcomes on which ECHO focuses, but the contributions of environmental factors to this risk are not well characterized. Three ECHO cohorts consist almost exclusively of individuals born very preterm. Data provided to ECHO from cohorts can be used to address hypotheses about (1) differential risks of chronic health and developmental conditions between individuals born very preterm and those born at term; (2) health disparities across social determinants of health; and (3) mechanisms linking early-life exposures and later-life outcomes among individuals born very preterm. IMPACT: The National Institutes of Health's Environmental Influences on Child Health Outcomes Program is conducting solution-oriented research on the links between children's environment and health. Three ECHO cohorts comprise study participants born very preterm; these cohorts have enrolled, to date, 1751 individuals born in 14 states in the U.S. in between April 2002 and March 2020. Extensive data are available on early-life environmental exposures and child outcomes related to neurodevelopment, asthma, obesity, and positive health. Data from ECHO preterm cohorts can be used to address questions about the combined effects of preterm birth and environmental exposures on child health outcomes.
Identifiants
pubmed: 35948605
doi: 10.1038/s41390-022-02230-5
pii: 10.1038/s41390-022-02230-5
pmc: PMC9363858
doi:
Types de publication
Journal Article
Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1161-1176Subventions
Organisme : NIEHS NIH HHS
ID : P30 ES010126
Pays : United States
Organisme : NIH HHS
ID : UG3 OD023320
Pays : United States
Organisme : NIH HHS
ID : UH3 OD023348
Pays : United States
Organisme : NIH HHS
ID : UH3 OD023347
Pays : United States
Organisme : NIH HHS
ID : UH3 OD023320
Pays : United States
Organisme : NICHD NIH HHS
ID : R03 HD101413
Pays : United States
Investigateurs
P B Smith
(PB)
K L Newby
(KL)
L P Jacobson
(LP)
C B Parker
(CB)
Informations de copyright
© 2022. The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc.
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