Current treatment strategies for seasonal allergic rhinitis: where are we heading?
Allergen immunotherapy
Personalized medicine
Seasonal allergic rhinitis
Symptomatic drugs
Treatment strategy
Journal
Clinical and molecular allergy : CMA
ISSN: 1476-7961
Titre abrégé: Clin Mol Allergy
Pays: England
ID NLM: 101152195
Informations de publication
Date de publication:
10 Aug 2022
10 Aug 2022
Historique:
received:
31
03
2022
accepted:
22
07
2022
entrez:
10
8
2022
pubmed:
11
8
2022
medline:
11
8
2022
Statut:
epublish
Résumé
Allergic rhinitis (AR) is very commonly caused by pollens. The symptoms of AR consist of sneezing, nasal congestion, rhinorrhea, nasal itching and airflow obstruction. The diagnosis has long been based on clinical history, skin prick tests and in vitro measurement of specific IgE, but the innovative approach of precision medicine has made diagnostic tools of much greater accuracy available. This review covers the advances in the treatment of seasonal AR concerning the drugs to be used according to the grade of disease and the characteristics of the patients, and the role of allergen immunotherapy (AIT), which is the only treatment capable of acting, in addition to the symptoms, on the cause of AR and therefore to modify its natural history. Drug treatment of AR include a large number of agents, the choice of which depends on the severity of the disease. AIT has high evidence of efficacy demonstrated by meta-analyses, and further improvement is currently apparent, as for diagnosis, applying the means of precision medicine. However, when AIT is performed in current practice, without the strict rules of controlled trials, long-term low adherence is a major problem to be solved.
Identifiants
pubmed: 35948975
doi: 10.1186/s12948-022-00176-x
pii: 10.1186/s12948-022-00176-x
pmc: PMC9367100
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
9Informations de copyright
© 2022. The Author(s).
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