Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and
Biomarkers
Long noncoding
RNA
Stomach neoplasms
Transcriptome
Whole exome sequencing
Journal
Iranian journal of basic medical sciences
ISSN: 2008-3866
Titre abrégé: Iran J Basic Med Sci
Pays: Iran
ID NLM: 101517966
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
12
12
2021
accepted:
27
04
2022
entrez:
11
8
2022
pubmed:
12
8
2022
medline:
12
8
2022
Statut:
ppublish
Résumé
Due to diagnosis of gastric cancer in advanced stages as well as its poor prognosis, finding biomarkers is essential. In this study, using the TCGA RNAseq data of gastric cancer patients, we evaluated the diagnostic value of lncRNAs that had differential expression. We evaluated Five lncRNAs had proper sensitivity and specificity and had target genes involved in cancer-related signaling pathways; however, they showed different expression patterns in TCGA data and The results of our study demonstrated that the five-lncRNAs
Identifiants
pubmed: 35949302
doi: 10.22038/IJBMS.2022.62181.13762
pmc: PMC9320203
doi:
Types de publication
Journal Article
Langues
eng
Pagination
704-714Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
Références
Nat Rev Genet. 2013 Aug;14(8):518
pubmed: 23817312
Cancer Res. 2006 Jun 1;66(11):5836-46
pubmed: 16740723
Cancer Cell Int. 2017 Jun 12;17:64
pubmed: 28615992
J Biol Chem. 2007 Aug 24;282(34):24731-42
pubmed: 17569660
Technol Cancer Res Treat. 2019 Jan 1;18:1533033819846638
pubmed: 31311442
Sci Signal. 2010 Feb 02;3(107):ra8
pubmed: 20124551
Oncol Rep. 2018 Sep;40(3):1554-1564
pubmed: 30015983
Sci Rep. 2015 Jun 22;5:11516
pubmed: 26096073
Mol Med Rep. 2017 Oct;16(4):4887-4894
pubmed: 28791375
RNA Biol. 2015;12(6):628-42
pubmed: 25864709
World J Gastroenterol. 2008 Feb 28;14(8):1149-55
pubmed: 18300338
Int J Oncol. 2019 Mar;54(3):1033-1042
pubmed: 30628639
Jpn J Clin Oncol. 2011 Mar;41(3):307-13
pubmed: 21242182
Clin Lab. 2019 Sep 1;65(9):
pubmed: 31532112
Biochem Biophys Res Commun. 2017 Aug 19;490(2):317-323
pubmed: 28619512
Nat Rev Genet. 2014 Jan;15(1):7-21
pubmed: 24296535
Front Genet. 2019 May 28;10:462
pubmed: 31191601
Cell. 2013 Jan 31;152(3):387-9
pubmed: 23374335
Med Sci Monit. 2016 Oct 11;22:3647-3657
pubmed: 27727196
Best Pract Res Clin Gastroenterol. 2015 Dec;29(6):895-905
pubmed: 26651251
Mol Cancer. 2017 Apr 26;16(1):82
pubmed: 28441948
J Exp Clin Cancer Res. 2018 Jul 27;37(1):171
pubmed: 30049286
Cancer Lett. 2015 Jan 28;356(2 Pt B):357-66
pubmed: 25444905
DNA Cell Biol. 2020 Jan;39(1):69-77
pubmed: 31702387
Microb Pathog. 2022 Jan;162:105304
pubmed: 34818576
Cancer Med. 2019 Nov;8(15):6768-6779
pubmed: 31517442
Mol Med Rep. 2018 Dec;18(6):5579-5593
pubmed: 30365077
PLoS Genet. 2019 Dec 27;15(12):e1008501
pubmed: 31881017
J Hematol Oncol. 2013 May 31;6:37
pubmed: 23725405
Cell Mol Life Sci. 2013 Dec;70(24):4785-94
pubmed: 23880895
Oncol Lett. 2016 Nov;12(5):4155-4160
pubmed: 27895785
Essays Biochem. 2013;54:113-26
pubmed: 23829531
Oncotarget. 2017 Aug 24;8(43):75007-75024
pubmed: 29088841
Curr Med Sci. 2019 Oct;39(5):694-701
pubmed: 31612385
Oncotarget. 2016 Nov 29;7(48):79596-79604
pubmed: 27793000
Eur Rev Med Pharmacol Sci. 2018 Sep;22(17):5576-5582
pubmed: 30229831
Int J Oncol. 2019 Jan;54(1):77-86
pubmed: 30431069
Life Sci. 2019 Jan 15;217:271-282
pubmed: 30557546
Clin Chim Acta. 2017 Nov;474:165-170
pubmed: 28942241
Nucleic Acids Res. 2021 Jan 8;49(D1):D605-D612
pubmed: 33237311
Int J Mol Sci. 2015 Mar 10;16(3):5467-96
pubmed: 25764159
Cancer Sci. 2018 Oct;109(10):3068-3079
pubmed: 30099826
Cold Spring Harb Perspect Biol. 2014 Aug 01;6(8):
pubmed: 25085913
Pharmazie. 2016 Oct 1;71(10):598-602
pubmed: 29441929
Neurobiol Dis. 2013 Oct;58:123-31
pubmed: 23726844
Nucleic Acids Res. 2019 Jan 8;47(D1):D140-D144
pubmed: 30380072
J Clin Invest. 2016 Aug 1;126(8):2775-82
pubmed: 27479746
Cell Stem Cell. 2015 May 7;16(5):504-16
pubmed: 25891907
J Cell Physiol. 2020 Apr;235(4):3189-3206
pubmed: 31595495
J Biol Chem. 2014 May 16;289(20):14066-74
pubmed: 24706748
Onco Targets Ther. 2019 Nov 27;12:10323-10334
pubmed: 31819516
Oncogene. 2012 Oct 25;31(43):4577-87
pubmed: 22266873