Highly Variable Expression of Merozoite Surface Protein MSPDBL2 in Diverse Plasmodium falciparum Clinical Isolates and Transcriptome Scans for Correlating Genes.
antigenic variation
blood culture
malaria
sexual development
transcription
Journal
mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231
Informations de publication
Date de publication:
30 08 2022
30 08 2022
Historique:
pubmed:
12
8
2022
medline:
3
9
2022
entrez:
11
8
2022
Statut:
ppublish
Résumé
The merozoite surface protein MSPDBL2 of Plasmodium falciparum is under strong balancing selection and is a target of naturally acquired antibodies. Remarkably, MSPDBL2 is expressed in only a minority of mature schizonts of any cultured parasite line, and
Identifiants
pubmed: 35950755
doi: 10.1128/mbio.01948-22
pmc: PMC9426457
doi:
Substances chimiques
Membrane Proteins
0
Protozoan Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0194822Subventions
Organisme : Medical Research Council
ID : MC_PC_20037
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S009760/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
Pays : United Kingdom
Organisme : Wellcome Trust (WT)
ID : 206194/Z/17/Z
Références
Nat Commun. 2022 May 30;13(1):3004
pubmed: 35637187
Science. 2015 Jan 23;347(6220):431-5
pubmed: 25502316
Sci Transl Med. 2018 Jun 27;10(447):
pubmed: 29950443
Genome Res. 2014 Sep;24(9):1433-44
pubmed: 25091627
Nucleic Acids Res. 2009 Jan;37(Database issue):D539-43
pubmed: 18957442
BMC Genomics. 2018 Dec 10;19(1):894
pubmed: 30526479
Nat Microbiol. 2018 Jun;3(6):687-697
pubmed: 29784978
Nat Commun. 2014 Sep 09;5:4754
pubmed: 25203297
PLoS Pathog. 2014 Mar 20;10(3):e1003943
pubmed: 24651270
Bioinformatics. 2015 Jan 15;31(2):166-9
pubmed: 25260700
Nat Commun. 2020 Mar 20;11(1):1503
pubmed: 32198457
Cell Host Microbe. 2014 Aug 13;16(2):165-176
pubmed: 25121746
J Biol Chem. 2016 Jul 1;291(27):14285-14299
pubmed: 27226583
Genome Biol. 2014;15(12):550
pubmed: 25516281
Mol Microbiol. 2010 Apr;76(1):12-24
pubmed: 20141604
Nat Biotechnol. 2014 Aug;32(8):819-21
pubmed: 24880488
PLoS One. 2009;4(4):e5410
pubmed: 19404387
Nature. 2014 Mar 13;507(7491):248-52
pubmed: 24572369
Nat Commun. 2019 May 13;10(1):2140
pubmed: 31086187
Mol Biol Evol. 2014 Jun;31(6):1490-9
pubmed: 24644299
Infect Immun. 2013 Oct;81(10):3835-42
pubmed: 23897617
Cell. 2021 Jun 24;184(13):3573-3587.e29
pubmed: 34062119
Genome Med. 2015 Feb 27;7(1):19
pubmed: 25722744
Bioinformatics. 2019 Aug 15;35(16):2865-2867
pubmed: 30590489
Nat Methods. 2018 May;15(5):359-362
pubmed: 29608555
BMC Genomics. 2015 Jun 13;16:454
pubmed: 26070627
PLoS Genet. 2012;8(11):e1002992
pubmed: 23133397
Nat Methods. 2020 Feb;17(2):137-145
pubmed: 31792435
Sci Rep. 2018 Oct 25;8(1):15763
pubmed: 30361631
BMC Genomics. 2011 Nov 30;12:587
pubmed: 22129310
Mol Biol Evol. 2010 Oct;27(10):2344-51
pubmed: 20457586
J Biol Chem. 2012 Sep 21;287(39):32922-39
pubmed: 22843685
Nature. 2007 Dec 13;450(7172):1091-5
pubmed: 18046333
Mol Cell Proteomics. 2010 Jul;9(7):1437-48
pubmed: 20332084
J Infect Dis. 2015 Aug 1;212(3):406-15
pubmed: 25646353
Science. 2018 Mar 16;359(6381):1259-1263
pubmed: 29590075
Science. 2019 Aug 23;365(6455):
pubmed: 31439762
Mol Biochem Parasitol. 2006 Oct;149(2):208-15
pubmed: 16837080
Sci Adv. 2020 Jun 10;6(24):eaaz5057
pubmed: 32577509
Infect Immun. 2015 Jun;83(6):2575-82
pubmed: 25870227
Science. 2018 May 4;360(6388):
pubmed: 29724925
Nat Methods. 2015 Apr;12(4):357-60
pubmed: 25751142
PLoS Biol. 2019 May 10;17(5):e3000264
pubmed: 31075098
Wellcome Open Res. 2019 Mar 29;4:58
pubmed: 31080894
Mol Biochem Parasitol. 2005 Sep;143(1):90-9
pubmed: 15996767
Nat Microbiol. 2019 Jan;4(1):144-154
pubmed: 30478286
Nat Commun. 2020 Dec 2;11(1):6159
pubmed: 33268801
Antimicrob Agents Chemother. 2013 Jul;57(7):2937-41
pubmed: 23587962