Stage IIA Skin Melanoma Treatment With ECHO-7 Oncolytic Virus Rigvir.

ECHO-7 virus Rigvir case report melanoma oncolytic virus peritumoral administration virotherapy

Journal

The Permanente journal
ISSN: 1552-5775
Titre abrégé: Perm J
Pays: United States
ID NLM: 9800474

Informations de publication

Date de publication:
14 09 2022
Historique:
pubmed: 12 8 2022
medline: 23 9 2022
entrez: 11 8 2022
Statut: ppublish

Résumé

Melanoma is a global problem due to the rising numbers of skin melanoma cases. Current treatment guidelines for patients with stage IIA melanoma recommend only observation after surgery. In this report, the authors describe a patient with stage IIA skin melanoma treated with surgery and Rigvir virotherapy. Two years after the patient discovered a brown spot on the right cheek, surgery was indicated because the mass had started to ulcerate. Rigvir virotherapy was applied both before and after surgery. Observations made more than 7 years after surgery indicated no signs of disease progression. This case report illustrates an early treatment approach. Neoadjuvant treatment for early-stage melanoma is gaining more interest in both scientific and medical communities; therefore, the authors believe it is relevant to share their observations.

Identifiants

pubmed: 35950985
doi: 10.7812/TPP/21.232
pmc: PMC9683754
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

139-144

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Auteurs

Ingrīda Čēma (I)

Institute of Stomatology, Rīga Stradiņš University, Riga, Latvia.
Oncology Centre of Latvia, Rīga East University Hospital, Riga, Latvia.

Regīna Kleina (R)

Medical faculty, Rīga Stradiņš University, Riga, Latvia.

Simona Doniņa (S)

Oncology Centre of Latvia, Rīga East University Hospital, Riga, Latvia.
Institute of Microbiology and Virology, Rīga Stradiņš University, Riga, Latvia.

Sergejs Isajevs (S)

Department of Pathology, Rīga Eastern Clinical University Hospital, Riga, Latvia.
Department of Pathology, Faculty of Medicine, University of Latvia, Riga, Latvia.

Tatjana Zablocka (T)

Department of Pathology, Rīga Eastern Clinical University Hospital, Riga, Latvia.
Department of Pathology, Faculty of Medicine, University of Latvia, Riga, Latvia.

Agnija Rasa (A)

R&D, Rigvir, Riga, Latvia.

Pēteris Alberts (P)

R&D, Rigvir, Riga, Latvia.

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