Context-specific emergence and growth of the SARS-CoV-2 Delta variant.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
10 2022
Historique:
received: 10 12 2021
accepted: 05 08 2022
pubmed: 12 8 2022
medline: 12 10 2022
entrez: 11 8 2022
Statut: ppublish

Résumé

The SARS-CoV-2 Delta (Pango lineage B.1.617.2) variant of concern spread globally, causing resurgences of COVID-19 worldwide

Identifiants

pubmed: 35952712
doi: 10.1038/s41586-022-05200-3
pii: 10.1038/s41586-022-05200-3
pmc: PMC9534748
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

154-160

Subventions

Organisme : NIAID NIH HHS
ID : U19 AI135995
Pays : United States
Organisme : Medical Research Council
ID : MC_PC_19012
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : R01 AI153044
Pays : United States
Organisme : Medical Research Council
ID : MR/S019510/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_19027
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 204311/Z/16/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 206298/Z/17/Z
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : 220885/Z/20/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 225288/Z/22/Z
Pays : United Kingdom
Organisme : European Research Council
ID : 725422
Pays : International
Organisme : Medical Research Council
ID : MR/W005611/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 203783/Z16/Z
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R015600/1
Pays : United Kingdom

Commentaires et corrections

Type : UpdateOf
Type : UpdateOf

Informations de copyright

© 2022. The Author(s).

Références

Vöhringer, H. S. et al. Genomic reconstruction of the SARS-CoV-2 epidemic in England. Nature 600, 506–511 (2021).
doi: 10.1038/s41586-021-04069-y
Earnest, R. et al. Comparative transmissibility of SARS-CoV-2 variants Delta and Alpha in New England, USA. Cell Rep. Med. 3, 100583 (2022).
doi: 10.1016/j.xcrm.2022.100583
Kupferschmidt, K. & Wadman, M. Delta variant triggers dangerous new phase in the pandemic. Science https://www.sciencemag.org/news/2021/06/delta-variant-triggers-dangerous-new-phase-pandemic (2021).
Vaidyanathan, G. Coronavirus variants are spreading in India—what scientists know so far. Nature 593, 321–322 (2021).
doi: 10.1038/d41586-021-01274-7
Elliott, P. et al. Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant. Science 374, eabl9551 (2021).
doi: 10.1126/science.abl9551
Twohig, K. A. et al. Hospital admission and emergency care attendance risk for SARS-CoV-2 Delta (B.1.617.2) compared with Alpha (B.1.1.7) variants of concern: a cohort study. Lancet Infect. Dis. 22, 35–42 (2021).
doi: 10.1016/S1473-3099(21)00475-8
Lucas, C. et al. Impact of circulating SARS-CoV-2 variants on mRNA vaccine-induced immunity. Nature 600, 523–529 (2021).
doi: 10.1038/s41586-021-04085-y
Challen, R. et al. Early epidemiological signatures of novel SARS-CoV-2 variants: establishment of B.1.617.2 in England. Preprint at bioRxiv https://doi.org/10.1101/2021.06.05.21258365 (2021).
Mishra, S. et al. Changing composition of SARS-CoV-2 lineages and rise of Delta variant in England. eClinicalMedicine 39, 101064 (2021).
doi: 10.1016/j.eclinm.2021.101064
Papa, G. et al. Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell–cell fusion. PLoS Pathog. 17, e1009246 (2021).
doi: 10.1371/journal.ppat.1009246
Mlcochova, P. et al. SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion. Nature 599, 114–119 (2021).
doi: 10.1038/s41586-021-03944-y
Cherian, S. et al. SARS-CoV-2 spike mutations, L452R, T478K, E484Q and P681R, in the second wave of COVID-19 in Maharashtra, India. Microorganisms 9, 1542 (2021).
doi: 10.3390/microorganisms9071542
Syed, A. M. et al. Rapid assessment of SARS-CoV-2 evolved variants using virus-like particles. Science 374, 1625–1632 (2021).
doi: 10.1126/science.abl6184
Investigation of SARS-CoV-2 Variants of Concern: Technical Briefings; https://www.gov.uk/government/publications/investigation-of-novel-sars-cov-2-variant-variant-of-concern-20201201 (Public Health England, 2020).
Bericht zu Virusvarianten von SARS-CoV-2 in Deutschland, 9 June 2021; https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/DESH/Bericht_VOC_2021-06-09 (Robert Koch Institut, 2021).
Abbott, S. & Funk, S. Estimating epidemiological quantities from repeated cross-sectional prevalence measurements. Preprint at medRxiv https://doi.org/10.1101/2022.03.29.22273101 (2022).
Dhar, M. S. et al. Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India. Science 374, 995–999 (2021).
doi: 10.1126/science.abj9932
du Plessis, L. et al. Establishment and lineage dynamics of the SARS-CoV-2 epidemic in the UK. Science 371, 708–712 (2021).
doi: 10.1126/science.abf2946
Lemey, P. et al. Accommodating individual travel history and unsampled diversity in Bayesian phylogeographic inference of SARS-CoV-2. Nat. Commun. 11, 5110 (2020).
doi: 10.1038/s41467-020-18877-9
SARS-CoV-2 Variants of Concern and Variants Under Investigation in England, Technical briefing 17; https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1001354/Variants_of_Concern_VOC_Technical_Briefing_17.pdf (Public Health England, 2021).
Kraemer, M. U. G. et al. Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B.1.1.7 emergence. Science 373, 889–895 (2021).
doi: 10.1126/science.abj0113
Covid-19: red list arrivals terminal opens at Heathrow Airport. BBC News https://www.bbc.co.uk/news/business-57310148 (2021).
Booking and Staying in a Quarantine Hotel If You’ve Been in a Red List Country https://www.gov.uk/guidance/booking-and-staying-in-a-quarantine-hotel-when-you-arrive-in-england (Department for Transport and Department of Health and Social Care, 2021).
COVID-19 Response—Spring 2021 (Summary); https://www.gov.uk/government/publications/covid-19-response-spring-2021/covid-19-response-spring-2021-summary (UK Cabinet Office, 2021).
Willis, R. Y. A. Coronavirus (COVID-19) Infection Survey, Characteristics of People Testing Positive for COVID-19, UK: 3 November 2021; https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/coronaviruscovid19infectionsurveycharacteristicsofpeopletestingpositiveforcovid19uk/3november2021 (Office for National Statistics, 2021).
Ferguson, N. M. B.1.617.2 Transmission in England: Risk Factors and Transmission Advantage https://www.gov.uk/government/publications/imperial-college-london-delta-b16172-transmission-in-england-risk-factors-and-transmission-advantage-1-june-2021 (Imperial College London, 2021).
Kalkauskas, A. et al. Sampling bias and model choice in continuous phylogeography: Getting lost on a random walk. PLoS Comput. Biol. 17, e1008561 (2021).
doi: 10.1371/journal.pcbi.1008561
Covid: Surge testing in Bedford due to Indian variant. BBC News https://www.bbc.co.uk/news/uk-england-beds-bucks-herts-57151534 (2021).
Jarvis, C. I. et al. CoMix study—Social Contact Survey in the UK; https://cmmid.github.io/topics/covid19/comix-reports.html (2020).
Grenfell, B. T., Bjørnstad, O. N. & Kappey, J. Travelling waves and spatial hierarchies in measles epidemics. Nature 414, 716–723 (2001).
doi: 10.1038/414716a
Lemey, P. et al. Untangling introductions and persistence in COVID-19 resurgence in Europe. Nature 595, 713–717 (2021).
doi: 10.1038/s41586-021-03754-2
Hodcroft, E. B. et al. Spread of a SARS-CoV-2 variant through Europe in the summer of 2020. Nature 595, 707–712 (2021).
doi: 10.1038/s41586-021-03677-y
Volz, E. et al. Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature 593, 266–269 (2021).
doi: 10.1038/s41586-021-03470-x
Tian, H. et al. An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China. Science 368, 638–642 (2020).
doi: 10.1126/science.abb6105
Park, S. W. et al. Roles of generation-interval distributions in shaping relative epidemic strength, speed, and control of new SARS-CoV-2 variants. Preprint at bioRxiv https://doi.org/10.1101/2021.05.03.21256545 (2021).
Kraemer, M. U. G. et al. Monitoring key epidemiological parameters of SARS-CoV-2 transmission. Nat. Med. 27, 1854–1855 (2021).
doi: 10.1038/s41591-021-01545-w
Relatório de Situação Sobre Diversidade Genética do Novo Coronavírus SARS-CoV-2 em Portugal—20-07-2021; http://www.insa.min-saude.pt/relatorio-de-situacao-sobre-diversidade-genetica-do-novo-coronavirus-sars-cov-2-em-portugal-20-07-2021/ (INSA, 2021).
Elliott, P. et al. Twin peaks: the Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England. Science 376, eabq441 (2022).
doi: 10.1126/science.abq4411
Madhi, S. A. et al. Population immunity and Covid-19 severity with Omicron variant in South Africa. N. Engl. J. Med. 386, 1314–1326 (2022).
doi: 10.1056/NEJMoa2119658
Ali, S. T. et al. Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions. Science 369, 1106–1109 (2020).
doi: 10.1126/science.abc9004
Mina, M. J. et al. A Global lmmunological Observatory to meet a time of pandemics. eLife 9, e58989 (2020).
doi: 10.7554/eLife.58989
Bastani, H. et al. Efficient and targeted COVID-19 border testing via reinforcement learning. Nature 599, 108–113 (2021).
doi: 10.1038/s41586-021-04014-z
O’Toole, Á. et al. Assignment of epidemiological lineages in an emerging pandemic using the pangolin tool. Virus Evol. 7, veab064 (2021).
doi: 10.1093/ve/veab064
Minh, B. Q. et al. IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era. Mol. Biol. Evol. 37, 1530–1534 (2020).
doi: 10.1093/molbev/msaa015
Sagulenko, P., Puller, V. & Neher, R. A. TreeTime: maximum-likelihood phylodynamic analysis. Virus Evol. 4, vex042 (2018).
doi: 10.1093/ve/vex042
Suchard, M. A. et al. Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10. Virus Evol. 4, vey016 (2018).
doi: 10.1093/ve/vey016
Hasegawa, M., Kishino, H. & Yano, T. Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. J. Mol. Evol. 22, 160–174 (1985).
doi: 10.1007/BF02101694
Gill, M. S. et al. Improving Bayesian population dynamics inference: a coalescent-based model for multiple loci. Mol. Biol. Evol. 30, 713–724 (2013).
doi: 10.1093/molbev/mss265
Rambaut, A., Drummond, A. J., Xie, D., Baele, G. & Suchard, M. A. Posterior summarization in Bayesian phylogenetics using Tracer 1.7. Syst. Biol. 67, 901–904 (2018).
doi: 10.1093/sysbio/syy032
Price, M. N., Dehal, P. S. & Arkin, A. P. FastTree 2—approximately maximum-likelihood trees for large alignments. PLoS ONE 5, e9490 (2010).
doi: 10.1371/journal.pone.0009490
Zuckerkandl, E. & Pauling, L. B. in Horizons in Biochemistry (eds Kasha, M. & Pullman, B.) 189–225 (Academic Press, 1962).
Pope, A. GB Postcode Area, Sector, District https://doi.org/10.7488/ds/1947 (Univ. of Edinburgh, 2017).
Lemey, P., Rambaut, A., Welch, J. J. & Suchard, M. A. Phylogeography takes a relaxed random walk in continuous space and time. Mol. Biol. Evol. 27, 1877–1885 (2010).
doi: 10.1093/molbev/msq067
SGSS and CHESS Data—NHS Digital; https://digital.nhs.uk/about-nhs-digital/corporate-information-and-documents/directions-and-data-provision-notices/data-provision-notices-dpns/sgss-and-sari-watch-data (NHS, 2021).
Kraemer, M. U. G. et al. Mapping global variation in human mobility. Nat Hum Behav 4, 800–810 (2020).
doi: 10.1038/s41562-020-0875-0
Wilson, R. J. et al. Differentially private SQL with bounded user contribution. Preprint at arXiv https://arxiv.org/abs/1909.01917 (2019).

Auteurs

John T McCrone (JT)

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.

Verity Hill (V)

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.

Sumali Bajaj (S)

Department of Zoology, University of Oxford, Oxford, UK.

Rosario Evans Pena (RE)

Department of Zoology, University of Oxford, Oxford, UK.

Ben C Lambert (BC)

College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, UK.

Rhys Inward (R)

Department of Zoology, University of Oxford, Oxford, UK.
MRC Centre of Global Infectious Disease Analysis, Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.

Samir Bhatt (S)

MRC Centre of Global Infectious Disease Analysis, Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.
Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Erik Volz (E)

MRC Centre of Global Infectious Disease Analysis, Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.

Christopher Ruis (C)

Molecular Immunity Unit, Department of Medicine, Cambridge University, Cambridge, UK.

Simon Dellicour (S)

Spatial Epidemiology Lab (SpELL), Université Libre de Bruxelles, Bruxelles, Belgium.
Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.

Guy Baele (G)

Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.

Alexander E Zarebski (AE)

Department of Zoology, University of Oxford, Oxford, UK.

Adam Sadilek (A)

Google, Mountain View, CA, USA.

Neo Wu (N)

Google, Mountain View, CA, USA.

Aaron Schneider (A)

Google, Mountain View, CA, USA.

Xiang Ji (X)

Department of Mathematics, School of Science and Engineering, Tulane University, New Orleans, LA, USA.

Jayna Raghwani (J)

Department of Zoology, University of Oxford, Oxford, UK.

Ben Jackson (B)

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.

Rachel Colquhoun (R)

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.

Áine O'Toole (Á)

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.

Thomas P Peacock (TP)

Department of Infectious Disease, Imperial College London, London, UK.
UK Health Security Agency, London, UK.

Kate Twohig (K)

UK Health Security Agency, London, UK.

Simon Thelwall (S)

UK Health Security Agency, London, UK.

Gavin Dabrera (G)

UK Health Security Agency, London, UK.

Richard Myers (R)

UK Health Security Agency, London, UK.

Nuno R Faria (NR)

Department of Zoology, University of Oxford, Oxford, UK.
MRC Centre of Global Infectious Disease Analysis, Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.
Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.

Carmen Huber (C)

BlueDot, Toronto, Ontario, Canada.

Isaac I Bogoch (II)

Divisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Department of Medicine, Division of Infectious Diseases, University of Toronto, Toronto, Ontario, Canada.

Kamran Khan (K)

BlueDot, Toronto, Ontario, Canada.
Department of Medicine, Division of Infectious Diseases, University of Toronto, Toronto, Ontario, Canada.
Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.

Louis du Plessis (L)

Department of Zoology, University of Oxford, Oxford, UK.
Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland.
Swiss Institute of Bioinformatics, Lausanne, Switzerland.

Jeffrey C Barrett (JC)

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.

David M Aanensen (DM)

Centre for Genomic Pathogen Surveillance, Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Wendy S Barclay (WS)

Department of Infectious Disease, Imperial College London, London, UK.

Meera Chand (M)

UK Health Security Agency, London, UK.

Thomas Connor (T)

Pathogen Genomics Unit, Public Health Wales NHS Trust, Cardiff, UK.
School of Biosciences, The Sir Martin Evans Building, Cardiff University, Cardiff, UK.
Quadram Institute, Norwich, UK.

Nicholas J Loman (NJ)

Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.

Marc A Suchard (MA)

Departments of Biostatistics, Biomathematics and Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.

Oliver G Pybus (OG)

Department of Zoology, University of Oxford, Oxford, UK. opybus@rvc.ac.uk.
Department of Pathobiology and Population Sciences, Royal Veterinary College London, London, UK. opybus@rvc.ac.uk.
Pandemic Sciences Institute, University of Oxford, Oxford, UK. opybus@rvc.ac.uk.

Andrew Rambaut (A)

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK. a.rambaut@ed.ac.uk.

Moritz U G Kraemer (MUG)

Department of Zoology, University of Oxford, Oxford, UK. moritz.kraemer@biology.ox.ac.uk.
Pandemic Sciences Institute, University of Oxford, Oxford, UK. moritz.kraemer@biology.ox.ac.uk.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH