Molecular Mechanisms of Diabetic Kidney Disease.
adaptive
cytokines
epigenetic
genetics
inflammatory
innate
innovation
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
04 Aug 2022
04 Aug 2022
Historique:
received:
04
07
2022
revised:
01
08
2022
accepted:
02
08
2022
entrez:
12
8
2022
pubmed:
13
8
2022
medline:
16
8
2022
Statut:
epublish
Résumé
The inflammatory component of diabetic kidney disease has become of great interest in recent years, with genetic and epigenetic variants playing a fundamental role in the initiation and progression of the disease. Cells of the innate immune system play a major role in the pathogenesis of diabetic kidney disease, with a lesser contribution from the adaptive immune cells. Other components such as the complement system also play a role, as well as specific cytokines and chemokines. The inflammatory component of diabetic kidney disease is of great interest and is an active research field, with the hope to find potential innovative therapeutic targets.
Identifiants
pubmed: 35955802
pii: ijms23158668
doi: 10.3390/ijms23158668
pmc: PMC9369345
pii:
doi:
Substances chimiques
Chemokines
0
Cytokines
0
Complement System Proteins
9007-36-7
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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