Cognitive and perceptual impairments in schizophrenia extend to other psychotic disorders but not schizotypy.
Goal maintenance
Psychosis
Relational memory
Schizophrenia
Schizotypy
Visual integration
Journal
Schizophrenia research. Cognition
ISSN: 2215-0013
Titre abrégé: Schizophr Res Cogn
Pays: United States
ID NLM: 101632223
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
17
03
2022
revised:
22
07
2022
accepted:
25
07
2022
entrez:
12
8
2022
pubmed:
13
8
2022
medline:
13
8
2022
Statut:
epublish
Résumé
Well characterised cognitive and perceptual impairments in schizophrenia may not be diagnostically specific with some studies suggesting no significant differences between psychotic disorders. This transdiagnostic ambiguity is paralleled in the boundary distinctions between psychotic disorders and the sub-threshold symptomatology of schizotypy. The current study used the CNTRACS test battery to explore if performance deficits in visual integration, relational memory and goal maintenance were specific to schizophrenia or extend to other psychotic disorders; and if task performance varied between individuals with schizophrenia and schizotypy in healthy adults. The sample consisted of healthy controls, and patients who met DSM-IV criteria for schizophrenia, other psychotic disorders and non-psychotic disorders who were tested in person; and an online sample of self-assessed healthy adults. No significant differences were found in performance between patients with schizophrenia and other psychotic disorders in contrast to non-psychotic disorders and healthy controls. The high schizotypy group performed better on the tasks compared to the other psychoses and schizophrenia groups. There were no differences in the healthy control group between individuals with high versus low schizotypy or between in-person and online task performance. These findings support the notion that cognitive and perceptual impairments in schizophrenia extend to other psychotic disorders but are discontinuous with schizotypy. This study provides insights into similarities between schizophrenia and other psychotic disorders with regards to the potential neural substrates underpinning these functions and supports the use of online tools for assessing domains of cognition and perception.
Identifiants
pubmed: 35959485
doi: 10.1016/j.scog.2022.100266
pii: S2215-0013(22)00031-2
pmc: PMC9361330
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100266Informations de copyright
© 2022 The Authors.
Déclaration de conflit d'intérêts
Authors report no potential conflicts of interest relevant to the current paper.
Références
Schizophr Bull. 2016 Jul;42(4):1056-67
pubmed: 26908926
Nat Genet. 2013 Oct;45(10):1150-9
pubmed: 23974872
Schizophr Bull. 2007 Sep;33(5):1131-7
pubmed: 17630405
NPJ Schizophr. 2015 Nov 04;1:15043
pubmed: 27336046
Neuropsychol Rev. 2018 Dec;28(4):509-533
pubmed: 30343458
Cogn Affect Behav Neurosci. 2016 Feb;16(1):164-75
pubmed: 26494483
Am J Psychiatry. 2009 Aug;166(8):863-74
pubmed: 19411370
Schizophr Bull. 2018 Oct 15;44(suppl_2):S556-S563
pubmed: 29474661
Schizophr Bull. 2012 Jan;38(1):103
pubmed: 22199091
Am J Psychiatry. 2009 Jul;166(7):749-52
pubmed: 19570935
Psychol Med. 2002 Feb;32(2):347-58
pubmed: 11866327
Schizophr Bull. 2012 Jan;38(1):125-34
pubmed: 22021658
Psychon Bull Rev. 1996 Jun;3(2):164-70
pubmed: 24213864
Schizophr Bull. 2015 Mar;41 Suppl 2:S417-26
pubmed: 25810056
Biol Psychiatry. 2010 Oct 1;68(7):617-24
pubmed: 20655509
Schizophr Bull. 1987;13(2):261-76
pubmed: 3616518
J Abnorm Psychol. 1999 Feb;108(1):120-33
pubmed: 10066998
Dialogues Clin Neurosci. 2019 Sep;21(3):239-248
pubmed: 31749648
Schizophr Bull. 2012 Jan;38(1):144-52
pubmed: 22101961
Neuropsychologia. 2014 Dec;65:221-33
pubmed: 25446968
Cogn Neuropsychiatry. 2015;20(1):53-63
pubmed: 25341444
Schizophr Res. 2019 Sep;211:36-43
pubmed: 31383512
JAMA Psychiatry. 2015 Sep;72(9):909-16
pubmed: 26200928
Schizophr Bull. 2009 Jan;35(1):136-52
pubmed: 18990711
Psychol Med. 2013 Dec;43(12):2535-45
pubmed: 23522057
Schizophr Bull. 2012 Jan;38(1):114-24
pubmed: 22124089
Psychol Assess. 2010 Mar;22(1):131-41
pubmed: 20230159
Clin Psychopharmacol Neurosci. 2018 Feb 28;16(1):7-17
pubmed: 29397662
Schizophr Bull. 2016 Sep;42(5):1149-57
pubmed: 27060129
Schizophr Bull. 2020 Jan 4;46(1):154-162
pubmed: 30953588
Neuropsychologia. 2015 Aug;75:469-80
pubmed: 26160288
J Abnorm Psychol. 2003 Feb;112(1):132-43
pubmed: 12653421