Conservative management versus systematic suture of isolated vaginal or first-degree perineal tears after delivery: A preliminary randomized efficacy trial.


Journal

Birth (Berkeley, Calif.)
ISSN: 1523-536X
Titre abrégé: Birth
Pays: United States
ID NLM: 8302042

Informations de publication

Date de publication:
09 2023
Historique:
revised: 14 07 2022
received: 27 09 2021
accepted: 15 07 2022
medline: 9 8 2023
pubmed: 13 8 2022
entrez: 12 8 2022
Statut: ppublish

Résumé

The objective of this study was to assess the preliminary efficacy and safety of conservative management compared with systematic suture in isolated vaginal or first-degree perineal tears after birth. We conducted a preliminary efficacy, open-label, randomized, controlled, and prospective trial. This study implemented Simon's 2-step plan (interim analysis and final analysis) to test the success rate of the digital compression strategy group. Primiparous women aged ≥18 years with isolated vaginal or first-degree perineal tears after spontaneous vaginal birth of a cephalic presenting term (≥37 weeks) neonate were randomly allocated to the conservative management (CM) group (digital compression if bleeding followed by suture if persistent bleeding) or a systematic suture (SS) group. The primary outcome was the success of the intervention 10 days after delivery, defined by pain as evaluated using a visual analog scale < 3, satisfactory healing defined by a REEDA score ≤ 2, and no bleeding or infection. Sexual well-being was assessed at 2 and 6 months postpartum. Among 861/2209 eligible women, 143 consenting women with a superficial perineal tear were randomized: 72 in the systematic suture group and 71 in the conservative management group. Success rate was 87.8% (90% CI [70.5-93.54]) (42/55) in the systematic suture group vs 90% (90% CI [78.3-93.8]) (53/61) in the conservative management group. The REEDA score was significantly higher in the systematic suture group (1.4 vs 0.9; P = 0.036). Perineal pain was significantly higher at day 1 in the systematic suture group (2.38 vs 1.69; P = 0.034). For the Female Sexual Functional Index score, no significant difference was found between the two groups at inclusion or at 2 and 6 months postpartum. Conservative management of superficial perineal tears shows an efficacy rate ≥90%. Women in the conservative management group had less pain at the 1st day follow-up and lower REEDA scores at the 10th day follow-up.

Sections du résumé

BACKGROUND
The objective of this study was to assess the preliminary efficacy and safety of conservative management compared with systematic suture in isolated vaginal or first-degree perineal tears after birth.
METHODS
We conducted a preliminary efficacy, open-label, randomized, controlled, and prospective trial. This study implemented Simon's 2-step plan (interim analysis and final analysis) to test the success rate of the digital compression strategy group. Primiparous women aged ≥18 years with isolated vaginal or first-degree perineal tears after spontaneous vaginal birth of a cephalic presenting term (≥37 weeks) neonate were randomly allocated to the conservative management (CM) group (digital compression if bleeding followed by suture if persistent bleeding) or a systematic suture (SS) group. The primary outcome was the success of the intervention 10 days after delivery, defined by pain as evaluated using a visual analog scale < 3, satisfactory healing defined by a REEDA score ≤ 2, and no bleeding or infection. Sexual well-being was assessed at 2 and 6 months postpartum.
RESULTS
Among 861/2209 eligible women, 143 consenting women with a superficial perineal tear were randomized: 72 in the systematic suture group and 71 in the conservative management group. Success rate was 87.8% (90% CI [70.5-93.54]) (42/55) in the systematic suture group vs 90% (90% CI [78.3-93.8]) (53/61) in the conservative management group. The REEDA score was significantly higher in the systematic suture group (1.4 vs 0.9; P = 0.036). Perineal pain was significantly higher at day 1 in the systematic suture group (2.38 vs 1.69; P = 0.034). For the Female Sexual Functional Index score, no significant difference was found between the two groups at inclusion or at 2 and 6 months postpartum.
CONCLUSIONS
Conservative management of superficial perineal tears shows an efficacy rate ≥90%. Women in the conservative management group had less pain at the 1st day follow-up and lower REEDA scores at the 10th day follow-up.

Identifiants

pubmed: 35960611
doi: 10.1111/birt.12671
doi:

Types de publication

Randomized Controlled Trial Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

513-524

Informations de copyright

© 2022 Wiley Periodicals LLC.

Références

NHS Maternity Statistics, England 2017-18. https://digital.nhs.uk/data-and-information/publications/statistical/nhs-maternity-statistics/2017-18. Accessed August 24, 2019.
Lundquist M, Olsson A, Nissen E, Norman M. Is it necessary to suture all lacerations after a vaginal delivery? Birth. 2000;27(2):79-85.
Gordon B, Mackrodt C, Fern E, Truesdale A, Ayers S, Grant A. The Ipswich childbirth study: 1. A randomised evaluation of two stage postpartum perineal repair leaving the skin unsutured. Br J Obstet Gynaecol. 1998;105(4):435-440. doi:10.1111/j.1471-0528.1998.tb10130.x
Fleming VEM, Hagen S, Niven C. Does perineal suturing make a difference? The SUNS trial. BJOG. 2003;110(7):684-689.
Elharmeel SM, Chaudhary Y, Tan S, Scheermeyer E, Hanafy A, van Driel ML. Surgical repair of spontaneous perineal tears that occur during childbirth versus no intervention. Cochrane Database Syst Rev. 2011;(8):CD008534. doi:10.1002/14651858.CD008534.pub2
Rosen R, Brown C, Heiman J, et al. The female sexual function index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26(2):191-208. doi:10.1080/009262300278597
Collins SL, Moore RA, McQuay HJ. The visual analogue pain intensity scale: what is moderate pain in millimetres? Pain. 1997;72(1-2):95-97. doi:10.1016/s0304-3959(97)00005-5
Davidson N. REEDA: evaluating postpartum healing. J Nurse Midwifery. 1974;19(2):6-8.
Forey P-L, Lallemant M, Bourtembourg-Matras A, et al. Impact of a selective use of episiotomy combined with Couder's maneuver for the perineal protection. Arch Gynecol Obstet. 2020;302(1):77-83. doi:10.1007/s00404-020-05572-9
Mottet N, Bonneaud M, Eckman-Lacroix A, Ramanah R, Riethmuller D. Active delivery of the anterior arm and incidence of second-degree perineal tears: a clinical practice evaluation. BMC Pregnancy Childbirth. 2017;17(1):141. doi:10.1186/s12884-017-1322-8

Auteurs

Marine Lallemant (M)

Department of Obstetrics and Gynecology, University Medical Center of Besancon, University of Franche-Comte, Besançon, France.
Applied Mechanics Department, FEMTO-ST Institute, University Bourgogne Franche-Comté, CNRS (UMR 6174), Besançon, France.

Aurélie D'Antona (A)

Department of Obstetrics and Gynecology, University Medical Center of Besancon, University of Franche-Comte, Besançon, France.

Chrystelle Vidal (C)

Centre d'investigation Clinique, INSERM CI 1431, University Medical Center of Besancon, Besançon, France.

Aude Bourtembourg (A)

Department of Obstetrics and Gynecology, University Medical Center of Besancon, University of Franche-Comte, Besançon, France.

Claire Toubin (C)

Department of Obstetrics and Gynecology, University Medical Center of Besancon, University of Franche-Comte, Besançon, France.

Malek Chehab (M)

Department of Obstetrics and Gynecology, University Medical Center of Besancon, University of Franche-Comte, Besançon, France.

Marie Vilchez (M)

Department of Obstetrics and Gynecology, University Medical Center of Besancon, University of Franche-Comte, Besançon, France.

Guillaume Boiteux (G)

Centre d'investigation Clinique, INSERM CI 1431, University Medical Center of Besancon, Besançon, France.

Rajeev Ramanah (R)

Department of Obstetrics and Gynecology, University Medical Center of Besancon, University of Franche-Comte, Besançon, France.
Nanomedecine Laboratory, INSERM EA4662, University of Franche-Comte, Besançon, France.

Lionel Pazart (L)

Centre d'investigation Clinique, INSERM CI 1431, University Medical Center of Besancon, Besançon, France.

Didier Riethmuller (D)

Department of Obstetrics and Gynecology, University Medical Center of Grenoble, Grenoble, France.

Nicolas Mottet (N)

Department of Obstetrics and Gynecology, University Medical Center of Besancon, University of Franche-Comte, Besançon, France.
Nanomedecine Laboratory, INSERM EA4662, University of Franche-Comte, Besançon, France.

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