Applying the Rapid OPPERA Algorithm to Predict Persistent Pain Outcomes Among a Cohort of Women Undergoing Breast Cancer Surgery.
Clustering
Pain
Postsurgical
Psychophysical
Psychosocial
Journal
The journal of pain
ISSN: 1528-8447
Titre abrégé: J Pain
Pays: United States
ID NLM: 100898657
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
received:
02
03
2022
revised:
27
07
2022
accepted:
31
07
2022
pubmed:
14
8
2022
medline:
10
12
2022
entrez:
13
8
2022
Statut:
ppublish
Résumé
Persistent postmastectomy pain after breast surgery is variable in duration and severity across patients, due in part to interindividual variability in pain processing. The Rapid OPPERA Algorithm (ROPA) empirically identified 3 clusters of patients with different risk of chronic pain based on 4 key psychophysical and psychosocial characteristics. We aimed to test this type of group-based clustering within in a perioperative cohort undergoing breast surgery to investigate differences in postsurgical pain outcomes. Women (N = 228) scheduled for breast cancer surgery were prospectively enrolled in a longitudinal observational study. Pressure pain threshold (PPT), anxiety, depression, and somatization were assessed preoperatively. At 2-weeks, 3, 6, and 12-months after surgery, patients reported surgical area pain severity, impact of pain on cognitive/emotional and physical functioning, and pain catastrophizing. The ROPA clustering, which used patients' preoperative anxiety, depression, somatization, and PPT scores, assigned patients to 3 groups: Adaptive (low psychosocial scores, high PPT), Pain Sensitive (moderate psychosocial scores, low PPT), and Global Symptoms (high psychosocial scores, moderate PPT). The Global Symptoms cluster, compared to other clusters, reported significantly worse persistent pain outcomes following surgery. Findings suggest that patient characteristic-based clustering algorithms, like ROPA, may generalize across diverse diagnoses and clinical settings, indicating the importance of "person type" in understanding pain variability. PERSPECTIVE: This article presents the practical translation of a previously developed patient clustering solution, based within a chronic pain cohort, to a perioperative cohort of women undergoing breast cancer surgery. Such preoperative characterization could potentially help clinicians apply personalized interventions based on predictions concerning postsurgical pain.
Identifiants
pubmed: 35963491
pii: S1526-5900(22)00371-6
doi: 10.1016/j.jpain.2022.07.012
pmc: PMC9729400
mid: NIHMS1829275
pii:
doi:
Types de publication
Observational Study
Randomized Controlled Trial
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
2003-2012Subventions
Organisme : NIGMS NIH HHS
ID : K23 GM110540
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM128691
Pays : United States
Informations de copyright
Copyright © 2022 United States Association for the Study of Pain, Inc. Published by Elsevier Inc. All rights reserved.
Références
Pain. 2014 Nov;155(11):2263-73
pubmed: 25139589
Pain. 2021 May 1;162(5):1528-1538
pubmed: 33259458
Anesthesiology. 2018 Sep;129(3):590-607
pubmed: 29738328
Pain. 2014 Feb;155(2):232-243
pubmed: 24099954
Can J Pain. 2019 Jul 30;3(2):49-58
pubmed: 35005419
J Pain. 2018 Dec;19(12):1461-1470
pubmed: 30025944
Pain. 2008 Aug 15;138(1):22-28
pubmed: 18079062
J Pain. 2019 May;20(5):540-556
pubmed: 30476655
JAMA. 2014 Jan 1;311(1):90-92
pubmed: 24381969
J Pain. 2016 Sep;17(9 Suppl):T1-9
pubmed: 27586826
J Pain. 2011 Jul;12(7):725-46
pubmed: 21435953
Pain. 2006 Aug;123(3):231-243
pubmed: 16697110
Pain. 2017 Apr;158 Suppl 1:S11-S18
pubmed: 27902569
JAMA. 2009 Nov 11;302(18):1985-92
pubmed: 19903919
Pain. 2015 Apr;156(4):609-617
pubmed: 25790453
Pain Med. 2017 May 1;18(5):947-958
pubmed: 28482098
J Clin Oncol. 2017 May 20;35(15):1660-1667
pubmed: 28524782
J Pain. 2012 Dec;13(12):1172-87
pubmed: 23182226
Pain Med. 2021 Aug 6;22(8):1767-1775
pubmed: 33560352
Pain Manag. 2014;4(6):445-59
pubmed: 25494696
Ann Surg Oncol. 2021 Sep;28(9):5015-5038
pubmed: 33452600
PLoS One. 2018 Feb 8;13(2):e0192623
pubmed: 29420607
Pain. 2013 May;154(5):660-668
pubmed: 23290256
Anesthesiology. 2021 Mar 1;134(3):363-365
pubmed: 33465232
Breast Cancer Res Treat. 2019 Oct;177(3):537-548
pubmed: 31270761
Pain. 2009 Nov;146(1-2):65-74
pubmed: 19665301
Breast Cancer (Auckl). 2021 Mar 24;15:1178223421995854
pubmed: 33994789
J Clin Epidemiol. 2010 Nov;63(11):1179-94
pubmed: 20685078
Eur J Oncol Nurs. 2014 Jun;18(3):242-53
pubmed: 24485012
Gen Hosp Psychiatry. 2010 Jul-Aug;32(4):345-59
pubmed: 20633738
JAMA Surg. 2017 May 1;152(5):485-493
pubmed: 28355428
J Psychosom Res. 2006 Apr;60(4):365-70
pubmed: 16581360
J Clin Oncol. 2012 Feb 10;30(5):539-47
pubmed: 22253460
J Pain. 2013 Oct;14(10):1185-95
pubmed: 23890847
Anesthesiology. 2021 Mar 1;134(3):421-434
pubmed: 33449996
Pain. 2010 Dec;151(3):722-731
pubmed: 20850220
Pain. 2016 Jun;157(6):1266-1278
pubmed: 26928952
Qual Life Res. 2017 May;26(5):1119-1128
pubmed: 27815821
Breast Cancer Res Treat. 2013 Apr;138(3):675-90
pubmed: 23553565
Pain. 2002 Apr;96(3):319-324
pubmed: 11973004
J Pain. 2020 Mar - Apr;21(3-4):294-305
pubmed: 31493489