Pathophysiology of Asthma-Chronic Obstructive Pulmonary Disease Overlap.
Asthma
Asthma-COPD overlap
COPD
Pathophysiology
Journal
Immunology and allergy clinics of North America
ISSN: 1557-8607
Titre abrégé: Immunol Allergy Clin North Am
Pays: United States
ID NLM: 8805635
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
entrez:
14
8
2022
pubmed:
15
8
2022
medline:
17
8
2022
Statut:
ppublish
Résumé
Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is a condition in which a person has clinical and biological features of both asthma and COPD. The pathophysiology behind the development of ACO is complex, with various inflammatory cells, cytokines, environmental factors, and architectural changes within the airways, all affecting a patient's clinical manifestation. A better understanding of the pathophysiologic mechanisms resulting in the development of ACO will help us to better identify potential drug targets and improve symptom burden and overall quality of life for patients living with ACO.
Identifiants
pubmed: 35965042
pii: S0889-8561(22)00030-3
doi: 10.1016/j.iac.2022.04.008
pmc: PMC10355375
mid: NIHMS1910482
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
521-532Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL125734
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007085
Pays : United States
Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure Dr F. Holguin is a member of the ASPEN trial adjudication committee, INSMED.
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