Asymmetric Synthesis of Nortropanes


Journal

ACS catalysis
ISSN: 2155-5435
Titre abrégé: ACS Catal
Pays: United States
ID NLM: 101562209

Informations de publication

Date de publication:
05 Aug 2022
Historique:
received: 06 05 2022
revised: 27 06 2022
entrez: 15 8 2022
pubmed: 16 8 2022
medline: 16 8 2022
Statut: ppublish

Résumé

Tropane derivatives are extensively used in medicine, but catalytic asymmetric methods for their synthesis are underexplored. Here, we report Rh-catalyzed asymmetric Suzuki-Miyaura-type cross-coupling reactions between a racemic

Identifiants

pubmed: 35966601
doi: 10.1021/acscatal.2c02259
pmc: PMC9361292
doi:

Types de publication

Journal Article

Langues

eng

Pagination

8995-9002

Informations de copyright

© 2022 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare the following competing financial interest(s): Oxford University Innovation has filed a patent application(PCT/GB2016/051612) with S.P.F. named as an inventor. Y.Z., F.W.G. and K.E.C. declare no competing financial interests.

Références

Org Lett. 2020 Feb 7;22(3):1034-1039
pubmed: 31951145
Pharmacol Rep. 2008 Jul-Aug;60(4):439-63
pubmed: 18799813
Nat Prod Rep. 1994 Aug;11(4):443-50
pubmed: 15200022
Org Lett. 2020 Apr 17;22(8):2991-2994
pubmed: 32216289
Chemistry. 2018 Mar 15;24(16):3994-3997
pubmed: 29384223
J Am Chem Soc. 2016 Jul 27;138(29):9145-57
pubmed: 27355973
J Org Chem. 2000 Jul 28;65(15):4773-5
pubmed: 10959895
Nat Commun. 2017 Jun 13;8:15762
pubmed: 28607510
Chem Cent J. 2015 May 24;9:30
pubmed: 26029252
Bioorg Med Chem Lett. 2002 May 6;12(9):1249-52
pubmed: 11965364
Nat Chem. 2015 Nov;7(11):935-9
pubmed: 26492015
J Am Chem Soc. 2018 Dec 5;140(48):16821-16833
pubmed: 30403847
Chem Rev. 2006 Jun;106(6):2434-54
pubmed: 16771455
Crit Care Clin. 2012 Oct;28(4):517-26
pubmed: 22998988
J Am Chem Soc. 2007 Aug 29;129(34):10312-3
pubmed: 17685525
Org Lett. 2004 Sep 16;6(19):3305-8
pubmed: 15355038
Angew Chem Int Ed Engl. 2019 Aug 26;58(35):12128-12132
pubmed: 31246358
Angew Chem Int Ed Engl. 2013 Dec 2;52(49):12892-6
pubmed: 24151037
Org Biomol Chem. 2021 May 5;19(17):3763-3775
pubmed: 33949549
Nat Protoc. 2019 Oct;14(10):2972-2985
pubmed: 31541227
Angew Chem Int Ed Engl. 2016 Sep 19;55(39):11834-9
pubmed: 27599657
Org Biomol Chem. 2014 Aug 21;12(31):5883-90
pubmed: 24984187
Alkaloids Chem Biol. 2019;81:151-233
pubmed: 30685050

Auteurs

Yan Zhang (Y)

Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom.

F Wieland Goetzke (FW)

Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom.

Kirsten E Christensen (KE)

Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom.

Stephen P Fletcher (SP)

Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom.

Classifications MeSH