Effects of sulforaphane intake on processing speed and negative moods in healthy older adults: Evidence from a randomized controlled trial.
biomarker
mood state
nutrition
processing speed
sulforaphane
Journal
Frontiers in aging neuroscience
ISSN: 1663-4365
Titre abrégé: Front Aging Neurosci
Pays: Switzerland
ID NLM: 101525824
Informations de publication
Date de publication:
2022
2022
Historique:
received:
27
04
2022
accepted:
29
06
2022
entrez:
15
8
2022
pubmed:
16
8
2022
medline:
16
8
2022
Statut:
epublish
Résumé
Recent studies have reported that sulforaphane (SFN) intake with cognitive training had positive effects on cognitive functions. However, it is still unknown whether SFN intake alone has beneficial effects on cognition as well as mood. We investigated whether a SFN intake intervention improved cognitive performance and mood states in healthy older adults. In a 12-week, double-blinded, randomized controlled trial (RCT), we randomly assigned 144 older adults to a SFN group or a placebo group. We asked the participants to take a supplement (SFN or placebo) for 12 weeks. We measured several cognitive functions, mood states, and biomarkers before and after the intervention period. The SFN group showed improvement in processing speed and a decrease in negative mood compared to the placebo group. In addition, the SFN group exhibited a higher SFN- These results indicate that nutrition interventions using SFN can have positive effects on cognitive functioning and mood in healthy older adults.
Sections du résumé
Background
UNASSIGNED
Recent studies have reported that sulforaphane (SFN) intake with cognitive training had positive effects on cognitive functions. However, it is still unknown whether SFN intake alone has beneficial effects on cognition as well as mood. We investigated whether a SFN intake intervention improved cognitive performance and mood states in healthy older adults.
Methods
UNASSIGNED
In a 12-week, double-blinded, randomized controlled trial (RCT), we randomly assigned 144 older adults to a SFN group or a placebo group. We asked the participants to take a supplement (SFN or placebo) for 12 weeks. We measured several cognitive functions, mood states, and biomarkers before and after the intervention period.
Results
UNASSIGNED
The SFN group showed improvement in processing speed and a decrease in negative mood compared to the placebo group. In addition, the SFN group exhibited a higher SFN-
Discussion
UNASSIGNED
These results indicate that nutrition interventions using SFN can have positive effects on cognitive functioning and mood in healthy older adults.
Identifiants
pubmed: 35966784
doi: 10.3389/fnagi.2022.929628
pmc: PMC9372582
doi:
Types de publication
Journal Article
Langues
eng
Pagination
929628Informations de copyright
Copyright © 2022 Nouchi, Hu, Ushida, Suganuma and Kawashima.
Déclaration de conflit d'intérêts
QH, YU, and HS were full-time employees of KAGOME CO., LTD. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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