Association Between Body Mass Index and Primary Open Angle Glaucoma in Three Cohorts.

Humans Optic Disk Glaucoma, Open-Angle / diagnosis Body Mass Index Retrospective Studies Cross-Sectional Studies Longitudinal Studies Canada Intraocular Pressure Glaucoma / diagnosis

Journal

American journal of ophthalmology
ISSN: 1879-1891
Titre abrégé: Am J Ophthalmol
Pays: United States
ID NLM: 0370500

Informations de publication

Date de publication:
01 2023
Historique:
received: 08 03 2022
revised: 04 08 2022
accepted: 04 08 2022
pubmed: 16 8 2022
medline: 17 12 2022
entrez: 15 8 2022
Statut: ppublish

Résumé

To evaluate the relationship between body mass index (BMI) and glaucoma progression. Multicohort observational study. This study combined a retrospective longitudinal analysis of suspect and early manifest primary open angle glaucoma cases from the Progression Risk of Glaucoma: RElevant SNPs with Significant Association (PROGRESSA) study with 2 replication cohorts from the UK Biobank and the Canadian Longitudinal Study of Ageing (CLSA). In the PROGRESSA study, multivariate analysis correlated BMI with longitudinal visual field progression in 471 participants. The BMI was then associated with glaucoma diagnosis and cross-sectional vertical cup-disc ratio (VCDR) measurements in the UK Biobank, and finally prospectively associated with longitudinal change in VCDR in the CLSA study. In the PROGRESSA study, a lower BMI conferred a faster rate of visual field progression (mean duration of monitoring (5.28 ± 1.80 years (10.6 ± 3.59 visits) (β 0.04 dB/year/SD95% CI [0.005, 0.069]; P = .013). In the UK Biobank, a 1 standard deviation lower BMI was associated with a worse cross-sectional VCDR (β -0.048/SD 95% CI [-0.056, 0.96]; P < .001) and a 10% greater likelihood of glaucoma diagnosis, as per specialist grading of retinal fundus imaging (OR 0.90 95% CI [0.84, 0.98]; P = .011). Similarly, a lower BMI was associated with a greater risk of glaucoma diagnosis as per International Classification of Disease data (OR 0.94/SD; 95% CI [0.91, 0.98]; P = .002). Body mass index was also positively correlated with intraocular pressure (β 0.11/SD; 95% CI [0.06, 0.15]; P < .001). Finally, a lower BMI was then associated with greater VCDR change in the CLSA (β -0.007/SD; 95% CI [-0.01, -0.001]; P = .023). Body mass index correlated with longitudinal and cross-sectional glaucomatous outcomes. This supports previous work illustrating a correlation between BMI and glaucoma.

Identifiants

DOI: 10.1016/j.ajo.2022.08.006 PMID: 35970205
pubmed: 35970205
pii: S0002-9394(22)00307-5
doi: 10.1016/j.ajo.2022.08.006
pii:
doi:

Types de publication

Observational Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

126-133

Subventions

Organisme : Medical Research Council
ID : MC_PC_17228
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_QA137853
Pays : United Kingdom

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Henry Marshall (H)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C). Electronic address: h.n.marshall@outlook.com.

Ella C Berry (EC)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Santiago Diaz Torres (SD)

QIMR Berghofer Medical Research Institute, Herston, Australia (S.D.T, S.M).

Sean Mullany (S)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C); QIMR Berghofer Medical Research Institute, Herston, Australia (S.D.T, S.M).

Joshua Schmidt (J)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Daniel Thomson (D)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Thi Thi Nguyen (TT)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Lachlan Sw Knight (LS)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Georgina Hollitt (G)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Ayub Qassim (A)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Antonia Kolovos (A)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Bronwyn Ridge (B)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Angela Schulz (A)

Faculty of Health and Medical Sciences, Macquarie University, Sydney, Australia (A.S, S.L.G).

Stewart Lake (S)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Richard A Mills (RA)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Ashish Agar (A)

Department of Ophthalmology, University of New South Wales, Sydney, Australia (A.A).

Anna Galanopoulos (A)

Discipline of Ophthalmology and Visual Sciences, University of Adelaide, Adelaide, Australia (A.G, R.J.C).

John Landers (J)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Paul R Healey (PR)

Centre for Vision Research, University of Sydney, Sydney, Australia (P.R.H).

Stuart L Graham (SL)

Faculty of Health and Medical Sciences, Macquarie University, Sydney, Australia (A.S, S.L.G).

Alex W Hewitt (AW)

Menzies Institute for Medical Research, University of Tasmania, Tasmania, Australia (A.W.H).

Robert J Casson (RJ)

Discipline of Ophthalmology and Visual Sciences, University of Adelaide, Adelaide, Australia (A.G, R.J.C).

Stuart MacGregor (S)

QIMR Berghofer Medical Research Institute, Herston, Australia (S.D.T, S.M).

Owen M Siggs (OM)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C); Garvan Institute of Medical Research, Sydney, Australia (O.M.S).

Jamie E Craig (JE)

From Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia (H.M, E.C.B, S.M, J.S, D.T, T.T.N, L.S.W.K, G.H, A.Q, A.K, B.R, S.L, R.A.M, J.L, O.M.S, J.E.C).

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Association Between Body Mass Index and...
questionsmedicales.fr › Organes des sens › Oeil › Rétine › Papille optique › Association Between Body Mass Index and...
questionsmedicales.fr › Maladies de l'oeil › Hypertension oculaire › Glaucome › Glaucome à angle ouvert › Association Between Body Mass Index and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Biométrie › Anthropométrie › Indice de masse corporelle › Association Between Body Mass Index and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Association Between Body Mass Index and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études transversales › Association Between Body Mass Index and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études longitudinales › Association Between Body Mass Index and...
questionsmedicales.fr › Régions géographiques › Amériques › Amérique du Nord › Canada › Association Between Body Mass Index and...
questionsmedicales.fr › Phénomènes physiologiques oculaires › Pression intraoculaire › Association Between Body Mass Index and...
questionsmedicales.fr › Maladies de l'oeil › Hypertension oculaire › Glaucome › Association Between Body Mass Index and...