Synthesis and characterization of d

Barbarea vulgaris aminorex d5-barbarin equine forensic science internal standard

Journal

Drug testing and analysis
ISSN: 1942-7611
Titre abrégé: Drug Test Anal
Pays: England
ID NLM: 101483449

Informations de publication

Date de publication:
Jan 2023
Historique:
revised: 12 08 2022
received: 19 04 2022
accepted: 12 08 2022
pubmed: 18 8 2022
medline: 26 1 2023
entrez: 17 8 2022
Statut: ppublish

Résumé

Based on structural similarities and equine administration experiments, Barbarin, 5-phenyl-2-oxazolidinethione from Brassicaceae plants, is a possible source of equine urinary identifications of aminorex, (R,S)-5-phenyl-4,5-dihydro-1,3-oxazol-2-amine, an amphetamine-related US Drug Enforcement Administration (DEA) controlled substance considered illegal in sport horses. We now report the synthesis and certification of d

Identifiants

pubmed: 35975356
doi: 10.1002/dta.3357
pmc: PMC10087961
doi:

Substances chimiques

barbarin 0
Aminorex 2SH16612I9
Protons 0
Oxazoles 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

42-46

Subventions

Organisme : The Equine Health and Welfare Alliance, Inc, Versailles, Kentucky,
Organisme : The National Horsemen's Benevolent and Protective Association and the Alabama, Arizona, Arkansas, Ontario, Canada; Charles Town, WV; Florida, Indiana, Iowa, Kentucky, Louisiana, Michigan, Minnesota, Nebraska, Ohio, Oklahoma, Oregon, Pennsylvania, Tampa Bay Downs, Florida, Texas, Washington State, and West Virginia Horsemen's Benevolent and Protective Associations
Organisme : The United States Trotting Association, Columbus, OH
Organisme : US Department of Agriculture
Organisme : National Institute of Food and Agriculture

Informations de copyright

© 2022 The Authors. Drug Testing and Analysis published by John Wiley & Sons Ltd.

Références

J Vet Pharmacol Ther. 2009 Apr;32(2):160-6
pubmed: 19290946
Drug Test Anal. 2020 Oct;12(10):1477-1482
pubmed: 32567235
Neurochem Int. 2014 Jul;73:32-41
pubmed: 24296074
Ir Vet J. 2010 Aug 01;63(8):498
pubmed: 21777496
Drug Test Anal. 2023 Jan;15(1):42-46
pubmed: 35975356
Ir Vet J. 2019 Dec 23;72:15
pubmed: 31890155
Anal Chim Acta. 2009 Apr 6;638(1):58-68
pubmed: 19298880
Clin Toxicol (Phila). 2015;53(7):604-8
pubmed: 26065363

Auteurs

Sucheta Kudrimoti (S)

The Department of Veterinary Science and the Maxwell H. Gluck Equine Research Center and the Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA.

Jacob Machin (J)

The Department of Veterinary Science and the Maxwell H. Gluck Equine Research Center and the Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA.

Adedamola S Arojojoye (AS)

Department of Chemistry, University of Kentucky, Lexington, Kentucky, USA.

Samuel G Awuah (SG)

Department of Chemistry, University of Kentucky, Lexington, Kentucky, USA.
Center for Pharmaceutical Research and Innovation, College of Pharmacy and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, USA.

Rodney Eisenberg (R)

Frontier BioPharm, LLC, Richmond, Kentucky, USA.

Clara Fenger (C)

Equine Integrated Medicine, Georgetown, Kentucky, USA.

George Maylin (G)

New York Drug Testing and Research Program, Ithaca, New York, USA.

Andreas F Lehner (AF)

Veterinary Diagnostic Lab Section of Toxicology, Michigan State University, Lansing, Michigan, USA.

Thomas Tobin (T)

The Department of Veterinary Science and the Maxwell H. Gluck Equine Research Center and the Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA.

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Classifications MeSH