Depression among patient with sickle cell disease: Prevalence and prediction.
Anemia
depression
sickle cell disease
Journal
Nigerian journal of clinical practice
ISSN: 1119-3077
Titre abrégé: Niger J Clin Pract
Pays: India
ID NLM: 101150032
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
entrez:
17
8
2022
pubmed:
18
8
2022
medline:
19
8
2022
Statut:
ppublish
Résumé
Depression is a widespread disorder with either an independent or interrelated relationship with chronic disease. This study aims to assess depression prevalence and its predictors among patients with sickle cell disease (SCD). This is a cross-sectional study conducted in Saudi Arabia where patients with SCD assessed for having depression through Patient Health Questionnaire (PHQ9). Depression was evaluated among 88 patients with SCD with a median age of 32.6 ± 11.8. Out of 88 patients, 44 (50%) participants had some form of depression. Out of those with depression, 25 (56.8%) had mild depression and 18 (40.9%) had moderate depression. However, there was a significant relationship between depression and the number of annual emergency visits, intensive care unit admissions, and frequency of blood transfusion (P-value < 0.05). There was no significant relationship between depression with neither hemoglobin nor HbS (P-value > 0.05). However, depression score found to be inversely proportional to the HbF level. Both gender and annual emergency visits were significantly related to depression (P-value = 0.01, 0.001. respectively). Depression is quite prevalent in patients with SCD though it is still being overlooked. Several clinical and laboratory indices found to be closely linked to depression. Constellations of these factors may help early recognition of depression and disease severity modulation.
Sections du résumé
Background
UNASSIGNED
Depression is a widespread disorder with either an independent or interrelated relationship with chronic disease.
Aim
UNASSIGNED
This study aims to assess depression prevalence and its predictors among patients with sickle cell disease (SCD).
Patients and Methods
UNASSIGNED
This is a cross-sectional study conducted in Saudi Arabia where patients with SCD assessed for having depression through Patient Health Questionnaire (PHQ9).
Results
UNASSIGNED
Depression was evaluated among 88 patients with SCD with a median age of 32.6 ± 11.8. Out of 88 patients, 44 (50%) participants had some form of depression. Out of those with depression, 25 (56.8%) had mild depression and 18 (40.9%) had moderate depression. However, there was a significant relationship between depression and the number of annual emergency visits, intensive care unit admissions, and frequency of blood transfusion (P-value < 0.05). There was no significant relationship between depression with neither hemoglobin nor HbS (P-value > 0.05). However, depression score found to be inversely proportional to the HbF level. Both gender and annual emergency visits were significantly related to depression (P-value = 0.01, 0.001. respectively).
Conclusion
UNASSIGNED
Depression is quite prevalent in patients with SCD though it is still being overlooked. Several clinical and laboratory indices found to be closely linked to depression. Constellations of these factors may help early recognition of depression and disease severity modulation.
Identifiants
pubmed: 35975375
pii: NigerJClinPract_2022_25_8_1274_353808
doi: 10.4103/njcp.njcp_50_22
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1274-1278Déclaration de conflit d'intérêts
None