Utilisation of complementary medicine in cancer patients and survivors: Expected benefits and its association to psychosocial factors.


Journal

European journal of cancer care
ISSN: 1365-2354
Titre abrégé: Eur J Cancer Care (Engl)
Pays: England
ID NLM: 9301979

Informations de publication

Date de publication:
Nov 2022
Historique:
revised: 07 07 2022
received: 15 09 2020
accepted: 02 08 2022
pubmed: 18 8 2022
medline: 30 11 2022
entrez: 17 8 2022
Statut: ppublish

Résumé

Previous research showed that various factors are associated with the use of complementary medicine (CM) in cancer patients. This study aimed to analyse the expected benefits of CM use in its association with medical, sociodemographic and psychosocial variables. In a cross-sectional survey, we assessed the use of CM, expected benefits of CM, depression and quality of life. An exploratory factor analysis (EFA) was performed. Multiple regression analysis was carried out with the factors derived from the EFA as dependent variables. Based on 292 cancer CM user, EFA revealed two factors: a supportive effect (SPE) and an antitumoral effect (ATE). In the multiple regression analysis, reduced emotional functioning and the diagnosis of breast cancer are associated with the higher expectation of a supportive effect of CM (p < 0.001), explaining 7.1% of the variance. Emotional functioning, educational level and metastases are associated with higher expectation of an antitumoral effect of CM (p < 0.001) and explained 14.8% of the variance. This study provides evidence that two overall domains (supportive effect and anti-tumoural effect) characterise the benefits of CM expected by cancer patients. Psychosocial and medical variables are associated with both domains, but explain only small proportion of the variance.

Identifiants

pubmed: 35977747
doi: 10.1111/ecc.13690
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e13690

Subventions

Organisme : Wellcome Trust
ID : 110149
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 110149
Pays : United Kingdom

Informations de copyright

© 2022 The Authors. European Journal of Cancer Care published by John Wiley & Sons Ltd.

Références

Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., Filiberti, A., Flechtner, H., Fleishman, S. B., Haes, J. C. J. M., Kaasa, S., Klee, M., Osoba, D., Razavi, D., Rofe, P. B., Schraub, S., Sneeuw, K., Sullivan, M., & Takeda, F. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365-376. https://doi.org/10.1093/jnci/85.5.365
Bauml, J. M., Chokshi, S., Schapira, M. M., Im, E. O., Li, S. Q., Langer, C. J., Ibrahim, S. A., & Mao, J. J. (2015). Do attitudes and beliefs regarding complementary and alternative medicine impact its use among patients with cancer? A cross-sectional survey. Cancer, 121(14), 2431-2438. https://doi.org/10.1002/cncr.29173
Correa-Velez, I., Clavarino, A., Barnett, A. G., & Eastwood, H. (2003). Use of complementary and alternative medicine and quality of life: Changes at the end of life. Palliative Medicine, 17(8), 695-703. https://doi.org/10.1191/0269216303pm834oa
Dişsiz, G., & Yilmaz, M. (2016). Complementary and alternative therapies and health literacy in cancer patients. Complementary Therapies in Clinical Practice, 23, 34-39. https://doi.org/10.1016/j.ctcp.2016.02.004
Evans, M. A., Shaw, A. R., Sharp, D. J., Thompson, E. A., Falk, S., Turton, P., & Thompson, T. (2007). Men with cancer: Is their use of complementary and alternative medicine a response to needs unmet by conventional care? European Journal of Cancer Care, 16(6), 517-525. https://doi.org/10.1111/j.1365-2354.2007.00786.x
Frenkel, M., Sierpina, V., & Sapire, K. (2015). Effects of complementary and integrative medicine on cancer survivorship. Current Oncology Reports, 17(5), 21.
Greenlee, H., DuPont-Reyes, M. J., Balneaves, L. G., Carlson, L. E., Cohen, M. R., Deng, G., Johnson, J. A., Mumber, M., Seely, D., Zick, S. M., & Boyce, L. M. (2017). Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment. CA: A Cancer Journal for Clinicians, 67(3), 194-232. https://doi.org/10.3322/caac.21397
Groenvold, M., Klee, M. C., Sprangers, M. A., & Aaronson, N. K. (1997). Validation of the EORTC QLQ-C30 quality of life questionnaire through combined qualitative and quantitative assessment of patient-observer agreement. Journal of Clinical Epidemiology, 50(4), 441-450. https://doi.org/10.1016/S0895-4356(96)00428-3
Gschwendtner, K. M., Klein, G., Guthlin, C., Holmberg, C., Horneber, M., & Weis, J. (2014). Importance of complementary medicine approaches for patients with prostate cancer. Der Urologe, 53(11), 1600-1609. https://doi.org/10.1007/s00120-014-3613-2
Guethlin, C., Walach, H., Naumann, J., Bartsch, H. H., & Rostock, M. (2010). Characteristics of cancer patients using homeopathy compared with those in conventional care: A cross-sectional study. Annals of Oncology, 21(5), 1094-1099. https://doi.org/10.1093/annonc/mdp421
Hammersen, F., Pursche, T., Fischer, D., Katalinic, A., & Waldmann, A. (2020). Use of complementary and alternative medicine among young patients with breast Cancer. Breast Care, 15, 163-170. https://doi.org/10.1159/000501193
Hlubocky, F. J., Ratain, M. J., Wen, M., & Daugherty, C. K. (2007). Complementary and alternative medicine among advanced cancer patients enrolled on phase I trials: A study of prognosis, quality of life, and preferences for decision making. Journal of Clinical Oncology, 25(5), 548-554. https://doi.org/10.1200/JCO.2005.03.9800
Horneber, M., Bueschel, G., Dennert, G., Less, D., Ritter, E., & Zwahlen, M. (2012). How many cancer patients use complementary and alternative medicine: A systematic review and metaanalysis. Integrative Cancer Therapies, 11(3), 187-203. https://doi.org/10.1177/1534735411423920
Horneber, M., van Ackeren, G., Fischer, F., Kappauf, H., & Birkmann, J. (2018). Addressing unmet information needs: Results of a clinician-led consultation service about complementary and alternative medicine for cancer patients and their relatives. Integrative Cancer Therapies, 17(4), 1172-1182. https://doi.org/10.1177/1534735418808597
Hübner, J., Prott, F. J., Micke, O., Muecke, R., Senf, B., Dennert, G., & Muenstedt, K. (2014). Online survey of cancer patients on complementary and alternative medicine. Oncology Research and Treatment, 37(6), 304-308. https://doi.org/10.1159/000362616
Hyodo, I., Amano, N., Eguchi, K., Narabayashi, M., Imanishi, J., Hirai, M., Nakano, T., & Takashima, S. (2005). Nationwide survey on complementary and alternative medicine in cancer patients in Japan. Journal of Clinical Oncology, 23(12), 2645-2654. https://doi.org/10.1200/JCO.2005.04.126
Kroenke, K., Spitzer, R. L., & Williams, J. B. (2001). The PHQ-9: Validity of a brief depression severity measure. Journal of General Internal Medicine, 16(9), 606-613. https://doi.org/10.1046/j.1525-1497.2001.016009606.x
Latte-Naor, S., Sidlow, R., Sun, L., Li, Q. S., & Mao, J. J. (2018). Influence of family on expected benefits of complementary and alternative medicine (CAM) in cancer patients. Supportive Care in Cancer, 26(6), 2063-2069. https://doi.org/10.1007/s00520-018-4053-0
Legenne, M., Chirac, A., Ruer, M., Reix, F., & Filbet, M. (2015). Perception of naturopathy for female patients with metastatic gynecological cancer: A qualitative study. Palliative & Supportive Care, 13(6), 1663-1668. https://doi.org/10.1017/S1478951515000553
Lopez, G., Mao, J. J., & Cohen, L. (2017). Integrative oncology. The Medical Clinics of North America, 101(5), 977-985. https://doi.org/10.1016/j.mcna.2017.04.011
Löwe, B., Kroenke, K., Herzog, W., & Gräfe, K. (2004). Measuring depression outcome with a brief self-report instrument: Sensitivity to change of the patient health questionnaire (PHQ-9). Journal of Affective Disorders, 81, 61-66.
Löwe, B., Unutzer, J., Callahan, C. M., Perkins, A. J., & Kroenke, K. (2004). Monitoring depression treatment outcomes with the patient health questionnaire-9. Medical Care, 42(12), 1194-1201. https://doi.org/10.1097/00005650-200412000-00006
Mao, J. J., Palmer, S. C., Desai, K., Li, S. Q., Armstrong, K., & Xie, S. X. (2012). Development and validation of an instrument for measuring attitudes and beliefs about complementary and alternative medicine (CAM) use among cancer patients. Evidence-based Complementary and Alternative Medicine, 2012, 798098.
Micke, O., Bruns, F., Glatzel, M., Schönekaes, K., Micke, P., Mücke, R., & Büntzel, J. (2009). Predictive factors for the use of complementary and alternative medicine (CAM) in radiation oncology. European Journal of Integrative Medicine, 1(1), 19-25. https://doi.org/10.1016/j.eujim.2009.02.001
Molassiotis, A., Fernadez-Ortega, P., Pud, D., Ozden, G., Scott, J. A., Panteli, V., Margulies, A., Browall, M., Magri, M., Selvekerova, S., Madsen, E., Milovics, L., Bruyns, I., Gudmundsdottir, G., Hummerston, S., Ahmad, A. M. A., Platin, N., Kearney, N., & Patiraki, E. (2005). Use of complementary and alternative medicine in cancer patients: A European survey. Annals of Oncology, 16(4), 655-663. https://doi.org/10.1093/annonc/mdi110
Montazeri, A., Sajadian, A., Ebrahimi, M., & Akbari, M. E. (2005). Depression and the use of complementary medicine among breast cancer patients. Supportive Care in Cancer, 13(5), 339-342. https://doi.org/10.1007/s00520-004-0709-z
Münstedt, K., Vogt, T., Rabanus, M. E., & Hubner, J. (2014). Wishes and beliefs of cancer patients regarding counseling on integrative medicine. Breast Care, 9(6), 416-420. https://doi.org/10.1159/000368428
Nissen, N., Lunde, A., Pedersen, C. G., & Johannessen, A. (2014). The use of complementary and alternative medicine after the completion of hosptial treatment of colorectal cancer: Findings from a questionnaire study in Denmark. BMC Complementary and Alternative Medicine, 14, 388. https://doi.org/10.1186/1472/6882-14-388
O'Connor, B. P. (2000). SPSS and SAS programs for determining the number of components using parallel analysis and Velicer's MAP test. Behavior Research Methods, Instruments, & Computers, 32(3), 396-402. https://doi.org/10.3758/BF03200807
Pedersen, C. G., Christensen, S., Jensen, A. B., & Zachariae, R. (2009). Prevalence, socio-demographic and clinical predictors of post-diagnostic utilisation of different types of complementary and alternative medicine (CAM) in a nationwide cohort of Danish women treated for primary breast cancer. European Journal of Cancer, 45(18), 3172-3181. https://doi.org/10.1016/j.ejca.2009.09.005
Pedersen, C. G., Christensen, S., Jensen, A. B., & Zachariae, R. (2013). Use of complementary and alternative medicine (CAM) and changes in depressive symptoms from 3 to 15 months after surgery for primary breast cancer: Results from a nationwide cohort study. Breast Cancer Research and Treatment, 141(2), 277-285. https://doi.org/10.1007/s10549-013-2680-1
Porter, M. C., & Diefenbach, M. A. (2009). Pushed and pulled: The role of affect and cognition in shaping CAM attitudes and behavior among men treated for prostate cancer. Journal of Health Psychology, 14(2), 288-296. https://doi.org/10.1177/1359105308100213
Rief, W., Nanke, A., Klaiberg, A., & Braehler, E. (2004). Base rates for panic and depression according to the brief patient health questionnaire: A population-based study. Journal of Affective Disorders, 82(2), 271-276. https://doi.org/10.1016/j.jad.2003.11.006
Risberg, T., & Jacobsen, B. K. (2003). The association between mental distress and the use of alternative medicine among cancer patients in North Norway. Quality of Life Research, 12(5), 539-544. https://doi.org/10.1023/A:1025063705413
Stein, K. D., Kaw, C., Crammer, C., & Gansler, T. (2009). The role of psychological functioning in the use of complementary and alternative methods among disease-free colorectal cancer survivors: A report from the American Cancer Society's studies of cancer survivors. Cancer, 115(18 Suppl), 4397-4408. https://doi.org/10.1002/cncr.24591
Verhoef, M. J., Balneaves, L. G., Boon, H. S., & Vroegindewey, A. (2005). Reasons for and characteristics associated with complementary and alternative medicine use among adult cancer patients: A systematic review. Integrative Cancer Therapies, 4(4), 274-286. https://doi.org/10.1177/1534735405282361
Waldmann, A., Schubert, D., & Katalinic, A. (2013). Normative data of the EORTC QLQ-C30 for the German population: A population-based survey. PLoS ONE, 8(9), e74149. https://doi.org/10.1371/journal.pone.0074149
Witt, C., Bartsch, H., Güthlin, C., Lamper, T. C., Längler, A., Ritter, C., Rostock, M., Schildmann, J., Weis, J., Wilhelm, M., & Horneber, M. (2017). Das Kompetenznetzwerk Komplementärmedizin in der Onkologie - KOKON. Ein Wissenschaftlicher Beitrag Zur Verbesserung der Versorgung. Forum, 32, 416-423. https://doi.org/10.1007/s12312-017-0311-1
Witt, C. M., Balneaves, L. G., Cardoso, M. J., Cohen, L., Greenlee, H., Johnstone, P., Kücük, Ö., Mailman, J., & Mao, J. J. (2017). A comprehensive definition for integrative oncology. Journal of the National Cancer Institute. Monographs, 52, lgx012-lgx.
Yun, H., Sun, L., & Mao, J. J. (2017). Growth of integrative medicine at leading Cancer centers between 2009 and 2016: A systematic analysis of NCI-designated Comprehensive cancer center websites. Journal of the National Cancer Institute. Monographs, 52, lgx004.

Auteurs

Joachim Weis (J)

Comprehensive Cancer Center University Hospital Freiburg, Freiburg, Germany.

Kathrin Gschwendtner (K)

Clinic for General internal Medicine and Psychosomatics, University Clinic Heidelberg, Heidelberg, Germany.

Corina Güthlin (C)

Institute of General Practice, Johann-Wolfgang-Goethe University Frankfurt am Main, Frankfurt, Germany.
Research Methodology and Project Management in General Practice, Institute for General Practice, Johann Wolfgang Goethe University in Frankfurt am Main, Frankfurt, Germany.
Johann Wolfgang Goethe-Universität Frankfurt am Main/Johann Wolfgang Goethe University, Frankfurt, Germany.

Christine Holmberg (C)

Institute of Social Medicine and Epidemiology, Brandenburg, Germany.
Brandenburg Medical School Theodor Fontane, Brandenburg, Germany.

Markus Horneber (M)

Department of Internal Medicine, Division of Pulmonology, Paracelsus Medical University, Clinic Center Nuremberg, Nuremberg, Germany.

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