Endarterectomy, Stenting, or Medical Treatment for Symptomatic Carotid Near-Occlusion: Results from CAOS, a Multicenter Registry Study.


Journal

AJNR. American journal of neuroradiology
ISSN: 1936-959X
Titre abrégé: AJNR Am J Neuroradiol
Pays: United States
ID NLM: 8003708

Informations de publication

Date de publication:
09 2022
Historique:
received: 15 03 2022
accepted: 17 06 2022
pubmed: 19 8 2022
medline: 30 12 2022
entrez: 18 8 2022
Statut: ppublish

Résumé

The treatment of symptomatic carotid near-occlusion is controversial. Our aim was to analyze the results of carotid endarterectomy and carotid artery stent placement in patients with symptomatic carotid near-occlusion and to identify factors related to technical failure, periprocedural complications, and restenosis. We conducted a multicenter, prospective nonrandomized study. Patients with angiography-confirmed carotid near-occlusion were included. We assessed the revascularization rate and periprocedural stroke or death. Twenty-four-month clinical and carotid imaging follow-up was performed, and rates of carotid restenosis or occlusion, ipsilateral stroke, and mortality were analyzed. Carotid artery stent placement, carotid endarterectomy, and medical treatment were compared. One hundred forty-one patients were included. Forty-four carotid artery stent placement and 23 carotid endarterectomy procedures were performed within 6 months after the event. Complete revascularization was achieved in 83.6%, 81.8% in the carotid artery stent placement group and 87% with carotid endarterectomy ( Carotid artery stent placement and carotid endarterectomy are associated with high rates of failure and periprocedural stroke. Carotid near-occlusion with full collapse appears to be associated with an increased risk of technical failure and restenosis. Carotid near-occlusion revascularization does not seem to reduce the risk of stroke at follow-up compared with medical treatment.

Sections du résumé

BACKGROUND AND PURPOSE
The treatment of symptomatic carotid near-occlusion is controversial. Our aim was to analyze the results of carotid endarterectomy and carotid artery stent placement in patients with symptomatic carotid near-occlusion and to identify factors related to technical failure, periprocedural complications, and restenosis.
MATERIALS AND METHODS
We conducted a multicenter, prospective nonrandomized study. Patients with angiography-confirmed carotid near-occlusion were included. We assessed the revascularization rate and periprocedural stroke or death. Twenty-four-month clinical and carotid imaging follow-up was performed, and rates of carotid restenosis or occlusion, ipsilateral stroke, and mortality were analyzed. Carotid artery stent placement, carotid endarterectomy, and medical treatment were compared.
RESULTS
One hundred forty-one patients were included. Forty-four carotid artery stent placement and 23 carotid endarterectomy procedures were performed within 6 months after the event. Complete revascularization was achieved in 83.6%, 81.8% in the carotid artery stent placement group and 87% with carotid endarterectomy (
CONCLUSIONS
Carotid artery stent placement and carotid endarterectomy are associated with high rates of failure and periprocedural stroke. Carotid near-occlusion with full collapse appears to be associated with an increased risk of technical failure and restenosis. Carotid near-occlusion revascularization does not seem to reduce the risk of stroke at follow-up compared with medical treatment.

Identifiants

pubmed: 35981762
pii: ajnr.A7617
doi: 10.3174/ajnr.A7617
pmc: PMC9451631
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1304-1310

Informations de copyright

© 2022 by American Journal of Neuroradiology.

Auteurs

A Garcia-Pastor (A)

From the Department of Neurology (A.G.-P., A.G.-N., E.C.-R.), Hospital General Universitario Gregorio Marañón, Madrid, Spain angarpas@yahoo.es.

A Gil-Núñez (A)

From the Department of Neurology (A.G.-P., A.G.-N., E.C.-R.), Hospital General Universitario Gregorio Marañón, Madrid, Spain.

J M Ramirez-Moreno (JM)

Department of Neurology (J.M.R.-M.), Hospital Universitario Infanta Cristina, Badajoz, Spain.

N González-Nafría (N)

Department of Neurology (N.G.-N., J.T.), Complejo Asistencial Universitario de León, Neurology, Leon, Spain.

J Tejada (J)

Department of Neurology (N.G.-N., J.T.), Complejo Asistencial Universitario de León, Neurology, Leon, Spain.

F Moniche (F)

Department of Neurology (F.M.), Hospital Universitario Virgen del Rocío, Sevilla, Sevilla, Spain.

J C Portilla-Cuenca (JC)

Department of Neurology (J.C.P.-C.), Hospital San Pedro Alcántara, Cáceres, Spain.

P Martínez-Sánchez (P)

Department of Neurology (P.M.-S., B.F.), Hospital Universitario La Paz, Madrid, Spain.

B Fuentes (B)

Department of Neurology (P.M.-S., B.F.), Hospital Universitario La Paz, Madrid, Spain.

M A Gamero-García (MA)

Department of Neurology (M.A.G.-G.), Hospital Universitario Virgen Macarena, Sevilla, Spain.

M A de Leciñana (MA)

Department of Neurology (M.A.d.L., J.M.), Hospital Universitario Ramón y Cajal, Madrid, Spain.

J Masjuan (J)

Department of Neurology (M.A.d.L., J.M.), Hospital Universitario Ramón y Cajal, Madrid, Spain.

D C Verge (DC)

Department of Neurology (D.C.V.), Corporació Sanitaria Parc Taulí, Sabadell, Spain.

Y Aladro (Y)

Department of Neurology (Y.A.), Hospital Universitario de Getafe, Getafe, Spain.

V Parkhutik (V)

Department of Neurology (V.P., A.L.), Hospital Universitari La Fe, Valencia, Spain.

A Lago (A)

Department of Neurology (V.P., A.L.), Hospital Universitari La Fe, Valencia, Spain.

A M de Arce-Borda (AM)

Department of Neurology (A.M.d.A.-B), Hospital Universitario de Donostia, Donostia, Spain.

M Usero-Ruiz (M)

Department of Neurology (M.U.-R.), Hospital Universitario de Valladolid, Valladolid, Spain.

R Delgado-Mederos (R)

Department of Neurology (R.D.-M.), Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

A Pampliega (A)

Department of Neurology (A.P.), Hospital General Univeristario de Alicante, Alicante, Spain.

Á Ximenez-Carrillo (Á)

Department of Neurology (Á.X.-C.), Hospital Universitario de La Princesa, Madrid, Spain.

M Bártulos-Iglesias (M)

Department of Neurology (M.B.-I.), Hospital Universitario de Burgos, Burgos, Spain.

E Castro-Reyes (E)

From the Department of Neurology (A.G.-P., A.G.-N., E.C.-R.), Hospital General Universitario Gregorio Marañón, Madrid, Spain.

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