Real-World Evaluation of Clinical Response and Long-Term Healthcare Resource Utilization Patterns Following Treatment with a Digital Therapeutic for Chronic Insomnia.
CBT-I
SHUTi
Somryst
chronic insomnia
cognitive behavioral therapy for insomnia
prescription digital therapeutic
Journal
ClinicoEconomics and outcomes research : CEOR
ISSN: 1178-6981
Titre abrégé: Clinicoecon Outcomes Res
Pays: New Zealand
ID NLM: 101560564
Informations de publication
Date de publication:
2022
2022
Historique:
received:
07
04
2022
accepted:
01
07
2022
entrez:
19
8
2022
pubmed:
20
8
2022
medline:
20
8
2022
Statut:
epublish
Résumé
This analysis evaluated insomnia severity and long-term impact on healthcare resource utilization (HCRU) and costs after treatment with Somryst Change from baseline in insomnia severity index (ISI) score was assessed using last observed ISI score. A pre/post analysis of claims data was conducted, comparing HCRU in patients with self-identified sleep problems who successfully initiated the therapeutic (index date) between June 1, 2016 and December 31, 2018. A total of 248 patients were analyzed (median age 56.5 years, 57.3% female, mean ISI score 19.13, 52.4% treated with sleep aid medications pre-index). After 9 weeks, mean ISI score declined by 37.2% from baseline (19.1 vs 12.0), 58.8% of patients achieved ISI responder status (ISI score improved by =>7; NNT: 1.7), and 26.6% of patients achieved insomnia remission (ISI score <8; NNT for remission: 3.8). After two-year follow-up, post-index events were reduced (compared to 2 years pre-index) for emergency department visits (-53%; IRR: 0.47; 95% CI 0.27, 0.82; In a real-world cohort of patients with chronic insomnia, treatment with a digital therapeutic delivering CBT-I was associated with reductions in insomnia severity, emergency department visits, and net costs.
Sections du résumé
Background and Objectives
UNASSIGNED
This analysis evaluated insomnia severity and long-term impact on healthcare resource utilization (HCRU) and costs after treatment with Somryst
Methods
UNASSIGNED
Change from baseline in insomnia severity index (ISI) score was assessed using last observed ISI score. A pre/post analysis of claims data was conducted, comparing HCRU in patients with self-identified sleep problems who successfully initiated the therapeutic (index date) between June 1, 2016 and December 31, 2018.
Results
UNASSIGNED
A total of 248 patients were analyzed (median age 56.5 years, 57.3% female, mean ISI score 19.13, 52.4% treated with sleep aid medications pre-index). After 9 weeks, mean ISI score declined by 37.2% from baseline (19.1 vs 12.0), 58.8% of patients achieved ISI responder status (ISI score improved by =>7; NNT: 1.7), and 26.6% of patients achieved insomnia remission (ISI score <8; NNT for remission: 3.8). After two-year follow-up, post-index events were reduced (compared to 2 years pre-index) for emergency department visits (-53%; IRR: 0.47; 95% CI 0.27, 0.82;
Conclusion
UNASSIGNED
In a real-world cohort of patients with chronic insomnia, treatment with a digital therapeutic delivering CBT-I was associated with reductions in insomnia severity, emergency department visits, and net costs.
Identifiants
pubmed: 35983014
doi: 10.2147/CEOR.S368780
pii: 368780
pmc: PMC9379126
doi:
Types de publication
Journal Article
Langues
eng
Pagination
537-546Informations de copyright
© 2022 Forma et al.
Déclaration de conflit d'intérêts
FF, FPT, XX, FFV, and YAM are employees of Pear Therapeutics (US), Inc. FPT also reports equity and employment from BeHealth Solutions, during the conduct of the study; and was a previous faculty member at institution (University of Virginia) that developed precursor (SHUTi) to this work. TGK and RB are employees of Market Access Consulting, Labcorp Drug Development, which participated in this study under contract with Pear Therapeutics (US), Inc. DCM is a consultant of Strategic Therapeutics, LLC, which participated in this study under contract with Pear Therapeutics (US), Inc. The authors report no other conflicts of interest in this work.
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