Atogepant for migraine.
Analgesic drugs
Antimigraine drugs
Atogepant
Calcitonin gene-related peptide (CGRP) receptor antagonists
Gepants
Migraine with aura
Migraine without aura
Journal
Drugs of today (Barcelona, Spain : 1998)
ISSN: 1699-3993
Titre abrégé: Drugs Today (Barc)
Pays: Spain
ID NLM: 101160518
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
entrez:
19
8
2022
pubmed:
20
8
2022
medline:
23
8
2022
Statut:
ppublish
Résumé
Atogepant is a selective oral, small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist that has been approved for preventive treatment of migraine. CGRP is a neuropeptide involved in vasodilation and cerebrovascular regulation. CGRP is the most potent vasoactive constituent of the cerebrovascular trigeminal neuronal system and has a key role in migraine. Medications targeting CGRP are being used as migraine preventive and abortive treatments.
Identifiants
pubmed: 35983926
pii: 3408815
doi: 10.1358/dot.2022.58.8.3408815
doi:
Substances chimiques
Analgesics
0
Calcitonin Gene-Related Peptide Receptor Antagonists
0
Piperidines
0
Pyridines
0
Pyrroles
0
Spiro Compounds
0
atogepant
7CRV8RR151
Calcitonin Gene-Related Peptide
JHB2QIZ69Z
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
399-405Informations de copyright
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