Improvements in Virologic Control Among PWH Over Time: Narrowing the Gap Between Those With and Without STIs.
Ending the HIV Epidemic
HIV
HIV transmission
Sexually transmitted infection
Viral load
Journal
AIDS and behavior
ISSN: 1573-3254
Titre abrégé: AIDS Behav
Pays: United States
ID NLM: 9712133
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
accepted:
24
07
2022
pmc-release:
01
02
2024
pubmed:
20
8
2022
medline:
11
2
2023
entrez:
19
8
2022
Statut:
ppublish
Résumé
Using the incidence of bacterial sexually transmitted infection (STI) as a surrogate for condomless sexual behavior, we assessed the association between STI and uncontrolled HIV replication among in-care persons with HIV (PWH) enrolled in a longitudinal HIV cohort study in the District of Columbia (the DC Cohort). Although STI occurrence initially correlated with higher HIV viral load (VL), this difference became more attenuated over time (2012-2016). This was true overall and among those with the greatest number of STIs [age 18-34, men who have sex with men (MSM)]. This likely reflects gains in population-wide virologic control through improved antiretroviral therapy and access to care, which helps mitigate the risk of HIV transmission.
Identifiants
pubmed: 35984609
doi: 10.1007/s10461-022-03802-6
pii: 10.1007/s10461-022-03802-6
pmc: PMC10176187
mid: NIHMS1888247
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
673-677Subventions
Organisme : NIAID NIH HHS
ID : P30 AI117970
Pays : United States
Organisme : NIAID NIH HHS
ID : R24 AI152598
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI069503
Pays : United States
Investigateurs
Lawrence D'Angelo
(L)
Natella Rakhmanina
(N)
Michael Kharfen
(M)
Michael Serlin
(M)
Princy Kumar
(P)
Vinay Bhandaru
(V)
Tsedenia Bezabeh
(T)
Nisha Grover-Fairchild
(N)
Lisa Mele
(L)
Susan Reamer
(S)
Alla Sapozhnikova
(A)
Greg Strylewicz
(G)
Marinella Temprosa
(M)
Naji Younes
(N)
Kevin Xiao
(K)
Morgan Byrne
(M)
Amanda Castel
(A)
Alan Greenberg
(A)
Maria Jaurretche
(M)
Paige Kulie
(P)
Anne Monroe
(A)
James Peterson
(J)
Bianca Stewart
(B)
Brittany Wilbourn
(B)
Yan Ma
(Y)
Hana Akselrod
(H)
Jhansi L Gajjala
(JL)
Sohail Rana
(S)
Michael Horberg
(M)
Ricardo Fernandez
(R)
Annick Hebou
(A)
Carl Dieffenbach
(C)
Henry Masur
(H)
Jose Bordon
(J)
Gebeyehu Teferi
(G)
Debra Benator
(D)
Maria Elena Ruiz
(ME)
Stephen Abbott
(S)
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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