Isoform a4 of the vacuolar ATPase a subunit promotes 4T1-12B breast cancer cell-dependent tumor growth and metastasis in vivo.

Animals Mice Cell Line, Tumor Cell Membrane / metabolism Protein Isoforms / metabolism Vacuolar Proton-Translocating ATPases / genetics Breast Neoplasms / enzymology Neoplasm Metastasis Mice, Inbred BALB C Cell Movement
breast cancer in vivo imaging tumor growth tumor metastasis vacuolar ATPase

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
10 2022
Historique:
received: 02 05 2022
revised: 11 08 2022
accepted: 15 08 2022
pubmed: 22 8 2022
medline: 3 11 2022
entrez: 21 8 2022
Statut: ppublish

Résumé

The vacuolar H

Identifiants

DOI: 10.1016/j.jbc.2022.102395 PMID: 35988642 PMC: PMC9508560
pubmed: 35988642
pii: S0021-9258(22)00838-9
doi: 10.1016/j.jbc.2022.102395
pmc: PMC9508560
pii:
doi:

Substances chimiques

Protein Isoforms 0
Vacuolar Proton-Translocating ATPases EC 3.6.1.-
Atp6v0a4 protein, mouse EC 3.6.1.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

102395

Subventions

Organisme : NCI NIH HHS
ID : R21 CA245172
Pays : United States

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that they have no conflicts of interest with the contents of this article.

Auteurs

Kevin Su (K)

Department of Pharmacology and Drug Development, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.

Michael P Collins (MP)

Department of Cellular, Molecular and Developmental Biology, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.

Christina M McGuire (CM)

Department of Biochemistry, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.

Mohammed A Alshagawi (MA)

Department of Pharmacology and Drug Development, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.

Mariam K Alamoudi (MK)

Department of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, USA.

Zhen Li (Z)

Department of Pharmacology and Drug Development, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.

Michael Forgac (M)

Department of Pharmacology and Drug Development, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA; Department of Cellular, Molecular and Developmental Biology, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA; Department of Biochemistry, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA; Department of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, USA. Electronic address: michael.forgac@tufts.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Isoformes de protéines › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Pompes ioniques › Transporteurs de cations › Pompes à protons › Proton-Translocating ATPases › Vacuolar Proton-Translocating ATPases › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Métastase tumorale › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée BALB C › Isoform a4 of the vacuolar ATPase a subunit...
questionsmedicales.fr › Phénomènes physiologiques › Mouvement cellulaire › Isoform a4 of the vacuolar ATPase a subunit...