A stress-blinded Atf1 can fully assemble heterochromatin in a RNAi-independent minimal mat locus but impairs directionality of
Epigenetics
Functional aspects of cell biology
Molecular biology
Molecular mechanism of gene regulation
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
19 Aug 2022
19 Aug 2022
Historique:
received:
21
01
2022
revised:
03
06
2022
accepted:
19
07
2022
entrez:
22
8
2022
pubmed:
23
8
2022
medline:
23
8
2022
Statut:
epublish
Résumé
The MAP kinase Sty1 phosphorylates and activates the transcription factor Atf1 in response to several stress conditions, which then shifts from a transcriptional repressor to an activator. Atf1 also participates in heterochromatin assembly at the
Identifiants
pubmed: 35992058
doi: 10.1016/j.isci.2022.104820
pii: S2589-0042(22)01092-6
pmc: PMC9389250
doi:
Types de publication
Journal Article
Langues
eng
Pagination
104820Informations de copyright
© 2022 The Author(s).
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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