Plasma cells arise from differentiation of clonal lymphocytes and secrete IgM in Waldenström macroglobulinemia.
Cancer
Cell biology
Immune system disorder
Immunology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
19 Aug 2022
19 Aug 2022
Historique:
received:
05
05
2022
revised:
16
06
2022
accepted:
25
07
2022
entrez:
22
8
2022
pubmed:
23
8
2022
medline:
23
8
2022
Statut:
epublish
Résumé
Waldenström macroglobulinemia (WM) is characterized by bone marrow infiltration with malignant lymphoplasmacytic cells (LPCs), a smaller population of plasma cells (PCs), and hypersecretion of IgM monoclonal protein. Here, we show that CD45
Identifiants
pubmed: 35992066
doi: 10.1016/j.isci.2022.104856
pii: S2589-0042(22)01128-2
pmc: PMC9389254
doi:
Types de publication
Journal Article
Langues
eng
Pagination
104856Informations de copyright
© 2022 The Author(s).
Déclaration de conflit d'intérêts
The authors declare no competing interests relevant to this manuscript. DT has received research funding from Janssen and Roche, and honoraria from CSL, Takeda, Roche, Janssen, Beigene, and EUSA.
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