Amyloid PET ordering practices in a memory disorders clinic.

This study assessed the ordering of amyloid positron emission tomography (PET) scans in a Veterans Affairs (VA) memory disorders clinic as part of routine clinical care, with possible implications for the extent to which ordering may occur outside of the VA in the future if covered by insurance. Clinical features predictive of ordering amyloid PET scans were retrospectively assessed; the percentage of patients who met appropriate use criteria were evaluated. Among 565 veterans, 34.9% of received an amyloid PET scan and 98.0% of these were consistent with appropriate use criteria. Patients with a PET were younger and more likely to have an initial diagnosis of Alzheimer's disease (AD). Of patients without an amyloid PET scan ordered, 64.4% would have met appropriate use criteria for amyloid PET. The majority of scans ordered were consistent with appropriate use criteria and more patients were eligible than received a scan. The current study's findings that approximately one-third of patients in a memory disorders clinic received an amyloid PET scan has implications for memory disorders clinics inside and outside of the US Veterans Health Administration.

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© 2022 The Authors. Alzheimer's & Dementia: Translational Research & Clinical Interventions published by Wiley Periodicals LLC on behalf of Alzheimer's Association.

Déclaration de conflit d'intérêts

Ana Vives‐Rodriguez, Kylie Schiloski, Anna Marin, Ryan Wang, Patrick Hajos, Prabhjyot Singh, Rachel Powsner, Katherine Turk, and Renee Decaro have no conflicts of interest to report. Andrew Budson has been a consultant for Eli Lilly, Corium, Cognito, and Sage; a grant recipient from Cyclerion; and a clinical trial investigator for Biogen, Eli Lilly, vTv therapeutics, and Cognito. Andrew E. Budson was supported by a VA Merit Award (CX001698). Andrew E. Budson and Katherine W. Turk were investigators on National Institutes of Health/National Institute on Aging (NIH/NIA) P30 (AG072978). Katherine W. Turk was supported by a VA Career Development Award (CX002065). Author disclosures are available in the supporting information.