Tuft Cells Are Present in Submandibular Glands Across Species.
chemosensation
immunology
secretion
taste receptors
Journal
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
ISSN: 1551-5044
Titre abrégé: J Histochem Cytochem
Pays: United States
ID NLM: 9815334
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
pubmed:
23
8
2022
medline:
1
10
2022
entrez:
22
8
2022
Statut:
ppublish
Résumé
Tuft cells are bottle-shaped, microvilli-projecting chemosensory cells located in the lining of a variety of epithelial tissues and, following their identification approximately 60 years ago, have been linked to immune system function in a variety of epithelia. Until recently, Tuft cells had not been convincingly demonstrated to be present in salivary glands with their detection by transmission electron microscopy only shown in a handful of earlier studies using rat salivary glands, and no follow-up work has been conducted to verify their presence in salivary glands of other species. Here, we demonstrate that Tuft cells are present in the submandibular glands of various species (i.e., mouse, pig and human) using transmission electron microscopy and confocal immunofluorescent analysis for the POU class 2 homeobox 3 (POU2F3), which is considered to be a master regulator of Tuft cell identity.
Identifiants
pubmed: 35993302
doi: 10.1369/00221554221120301
pmc: PMC9527474
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
659-667Références
Nature. 2016 Jan 14;529(7585):226-30
pubmed: 26762460
Chem Senses. 2015 Jul;40(6):413-25
pubmed: 25940069
J Clin Invest. 2014 Mar;124(3):1393-405
pubmed: 24531552
J Appl Physiol (1985). 2006 Apr;100(4):1103-4
pubmed: 16540706
J Physiol. 2004 Jul 15;558(Pt 2):561-75
pubmed: 15146045
Acta Pathol Microbiol Scand Suppl. 1956;39(Suppl 111):72-3
pubmed: 13372265
Science. 2016 Mar 18;351(6279):1329-33
pubmed: 26847546
Sci Immunol. 2021 Dec 24;6(66):eabj0474
pubmed: 34932383
Prog Neurobiol. 2010 May;91(1):77-89
pubmed: 20138111
Antimicrob Agents Chemother. 2005 Sep;49(9):3883-8
pubmed: 16127066
J Comp Neurol. 2008 Aug 10;509(5):514-25
pubmed: 18537122
Anat Rec. 1997 Jul;248(3):325-31
pubmed: 9214549
Biosci Biotechnol Biochem. 2013;77(10):2154-6
pubmed: 24096675
Sci Rep. 2020 Jun 1;10(1):8877
pubmed: 32483224
Pflugers Arch. 2021 Nov;473(11):1713-1722
pubmed: 34635955
PLoS One. 2017 Dec 7;12(12):e0189340
pubmed: 29216297
Annu Rev Immunol. 2019 Apr 26;37:47-72
pubmed: 30379593
Sci Rep. 2019 Nov 25;9(1):17466
pubmed: 31767912
Immunity. 2018 Jul 17;49(1):33-41.e7
pubmed: 30021144
Biol Res. 2015 Oct 31;48:61
pubmed: 26520150
Nat Neurosci. 2011 Jun;14(6):685-7
pubmed: 21572433
Cell Tissue Res. 2021 Jul;385(1):21-35
pubmed: 33616728
Genes Dev. 2018 Jul 1;32(13-14):915-928
pubmed: 29945888
Sci Rep. 2016 Nov 23;6:37667
pubmed: 27876863
Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3210-5
pubmed: 20133764
J Clin Med. 2020 Dec 18;9(12):
pubmed: 33353023
Front Physiol. 2020 Feb 14;11:88
pubmed: 32116793
Nature. 2016 Jan 14;529(7585):221-5
pubmed: 26675736
J Vis Exp. 2015 Jul 19;(101):e52918
pubmed: 26273796
Curr Opin Endocrinol Diabetes Obes. 2012 Feb;19(1):19-25
pubmed: 22157399
Stem Cells. 2014 Mar;32(3):822-7
pubmed: 24123696
Histochem Cell Biol. 2012 Apr;137(4):483-97
pubmed: 22261922
Sci Immunol. 2018 Oct 5;3(28):
pubmed: 30291131
Auton Neurosci. 2007 Apr 30;133(1):3-18
pubmed: 17157080
BMC Neurosci. 2014 Jan 16;15:13
pubmed: 24428937
Nature. 2017 Nov 16;551(7680):333-339
pubmed: 29144463
Chem Senses. 2007 Jan;32(1):41-9
pubmed: 17030556
Nat Commun. 2021 Feb 5;12(1):836
pubmed: 33547321
Z Zellforsch Mikrosk Anat. 1956;44(4):345-412
pubmed: 13353477
Sci Immunol. 2020 Jan 17;5(43):
pubmed: 31953256
Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8981-6
pubmed: 12857948
Cell Tissue Res. 1981;218(2):403-20
pubmed: 7020950
Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6631-4
pubmed: 8692869
Cell Tissue Res. 2014 Dec;358(3):737-48
pubmed: 25300645
Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9478-83
pubmed: 21606356
Front Oral Health. 2021 Nov 02;2:767568
pubmed: 35048069