ZNFX-1 keeps RNAi in the loop.

Animals Caenorhabditis elegans / genetics Caenorhabditis elegans Proteins / metabolism RNA Interference RNA, Double-Stranded / metabolism RNA, Small Interfering / genetics

Journal

Developmental cell
ISSN: 1878-1551
Titre abrégé: Dev Cell
Pays: United States
ID NLM: 101120028

Informations de publication

Date de publication:
22 08 2022
Historique:
entrez: 23 8 2022
pubmed: 24 8 2022
medline: 26 8 2022
Statut: ppublish

Résumé

In a recent issue of Nature Cell Biology, Ouyang et al. examined the dynamics of double-stranded-RNA-induced gene-silencing across the Caenorhabditis elegans germline and in different subcellular locations. They distinguished among several small RNA amplification loops which complement each other and only together achieve full gene expression inhibition.

Identifiants

DOI: 10.1016/j.devcel.2022.07.010 PMID: 35998582
pubmed: 35998582
pii: S1534-5807(22)00527-5
doi: 10.1016/j.devcel.2022.07.010
pii:
doi:

Substances chimiques

Caenorhabditis elegans Proteins 0
RNA, Double-Stranded 0
RNA, Small Interfering 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

1920-1921

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Itai Rieger (I)

Department of Neurobiology, Wise Faculty of Life Sciences and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel. Electronic address: itairieger@gmail.com.

Oded Rechavi (O)

Department of Neurobiology, Wise Faculty of Life Sciences and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel. Electronic address: odedrechavi@gmail.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › ZNFX-1 keeps RNAi in the loop.
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Helminthes › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Caenorhabditis › Caenorhabditis elegans › ZNFX-1 keeps RNAi in the loop.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines d'helminthes › Protéines de Caenorhabditis elegans › ZNFX-1 keeps RNAi in the loop.
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Interférence par ARN › ZNFX-1 keeps RNAi in the loop.
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › ARN double brin › ZNFX-1 keeps RNAi in the loop.
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › Petit ARN interférent › ZNFX-1 keeps RNAi in the loop.