The position of renal denervation in treatment of hypertension: an expert consensus statement.
Consensus
Hypertension
Netherlands
Patient care
Sympathectomy
Journal
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
ISSN: 1568-5888
Titre abrégé: Neth Heart J
Pays: Netherlands
ID NLM: 101095458
Informations de publication
Date de publication:
Jan 2023
Jan 2023
Historique:
accepted:
01
08
2022
pubmed:
25
8
2022
medline:
25
8
2022
entrez:
24
8
2022
Statut:
ppublish
Résumé
Hypertension is an important risk factor for cardiovascular disease. In the Netherlands, there are approximately 2.8 million people with hypertension. Despite treatment recommendations including lifestyle changes and antihypertensive drugs, most patients do not meet guideline-recommended blood pressure (BP) targets. In order to improve BP control and lower the risk of subsequent cardiovascular events, renal sympathetic denervation (RDN) has been introduced and studied as a non-pharmacological approach. While early data on the efficacy of RDN showed conflicting results, improvements in treatment protocols and study design resulted in robust new evidence supporting the potential of the technology to improve patient care in hypertensive subjects. Recently, 5 randomised sham-controlled trials demonstrated the safety and efficacy of the technology. Modelling studies have further shown that RDN is cost-effective in the Dutch healthcare setting. Given the undisputable disease burden along with the shortcomings of current therapeutic options, we postulate a new, clearly framed indication for RDN as an adjunct in the treatment of hypertension. The present consensus statement summarises current guideline-recommended BP targets, proposed workup and treatment for hypertension, and position of RDN for those patients with primary hypertension who do not meet guideline-recommended BP targets (see central illustration).
Identifiants
pubmed: 36001280
doi: 10.1007/s12471-022-01717-4
pii: 10.1007/s12471-022-01717-4
pmc: PMC9807711
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
3-11Informations de copyright
© 2022. The Author(s).
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