Targeting the tamoxifen receptor within sodium channels to block osteoarthritic pain.

Action Potentials Ganglia, Spinal Humans Nociceptors Pain / drug therapy Tamoxifen / pharmacology Voltage-Gated Sodium Channels
CP: Neuroscience DRG neurons molecular pharmacology nociceptors osteoarthritis pain sodium channel

Journal

Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691

Informations de publication

Date de publication:
23 08 2022
Historique:
received: 03 11 2021
revised: 29 06 2022
accepted: 01 08 2022
entrez: 24 8 2022
pubmed: 25 8 2022
medline: 27 8 2022
Statut: ppublish

Résumé

Voltage-gated sodium channels (Na

Identifiants

DOI: 10.1016/j.celrep.2022.111248 PMID: 36001977 PMC: PMC9523973
pubmed: 36001977
pii: S2211-1247(22)01066-X
doi: 10.1016/j.celrep.2022.111248
pmc: PMC9523973
mid: NIHMS1837894
pii:
doi:

Substances chimiques

Voltage-Gated Sodium Channels 0
Tamoxifen 094ZI81Y45

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

111248

Subventions

Organisme : NIGMS NIH HHS
ID : T32 GM008382
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR077019
Pays : United States
Organisme : NIAMS NIH HHS
ID : P30 AR079206
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK123463
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK131118
Pays : United States

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Références

J Bone Joint Surg Am. 2018 Apr 18;100(8):666-677
pubmed: 29664853
Mol Cell. 2021 Mar 18;81(6):1160-1169.e5
pubmed: 33503406
Mol Pharmacol. 1985 May;27(5):549-58
pubmed: 2581124
Osteoarthritis Cartilage. 2022 Feb;30(2):184-195
pubmed: 34534661
Mol Pharmacol. 2019 Oct;96(4):485-492
pubmed: 31391290
Osteoarthritis Cartilage. 2007 Sep;15(9):1061-9
pubmed: 17470400
Biochem Pharmacol. 1973 Dec 1;22(23):3099-108
pubmed: 4202581
Clin Rheumatol. 2009 Jul;28(7):749-56
pubmed: 19252817
JCI Insight. 2018 Mar 22;3(6):
pubmed: 29563338
J Gen Physiol. 2005 May;125(5):465-81
pubmed: 15824190
Brain Res Mol Brain Res. 2002 Mar 28;99(2):102-13
pubmed: 11978401
J Biol Chem. 2018 Oct 26;293(43):16546-16558
pubmed: 30219789
Elife. 2017 May 16;6:
pubmed: 28508747
Curr Top Membr. 2016;78:39-64
pubmed: 27586280
Steroids. 2007 Nov;72(13):829-42
pubmed: 17765940
Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8963-8
pubmed: 9671787
J Gen Physiol. 1964 May;47:965-74
pubmed: 14155438
Mol Pain. 2005 Aug 22;1:24
pubmed: 16111501
Annu Rev Physiol. 2001;63:871-94
pubmed: 11181979
Elife. 2020 May 22;9:
pubmed: 32441256
Hum Gene Ther. 2005 Feb;16(2):271-7
pubmed: 15761266
Mol Pain. 2016 Jul 05;12:
pubmed: 27385723
PLoS One. 2014 Sep 04;9(9):e105895
pubmed: 25188265
Arthritis Care Res (Hoboken). 2020 Feb;72(2):149-162
pubmed: 31908149
Nature. 2016 Sep 1;537(7618):117-121
pubmed: 27556947
Nat Rev Rheumatol. 2019 Feb;15(2):77-90
pubmed: 30498258
Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19444-9
pubmed: 23115331
Neuroscience. 1994 May;60(1):245-54
pubmed: 8052416
Nature. 2011 Jul 10;475(7356):353-8
pubmed: 21743477
Adv Drug Deliv Rev. 2006 May 20;58(2):226-42
pubmed: 16574267
Expert Opin Ther Targets. 2016 Aug;20(8):975-83
pubmed: 26941184
Nat Rev Drug Discov. 2011 Jun;10(6):428-38
pubmed: 21629293
Cell. 2020 Jan 9;180(1):122-134.e10
pubmed: 31866066
Arthritis Rheumatol. 2017 Jul;69(7):1429-1439
pubmed: 28380690
Bioorg Med Chem. 2018 Aug 15;26(15):4428-4440
pubmed: 30078609
Brain. 2005 Aug;128(Pt 8):1847-54
pubmed: 15958509
Bioorg Med Chem Lett. 2010 May 15;20(10):3036-8
pubmed: 20400308
J Mol Biol. 2021 Aug 20;433(17):166967
pubmed: 33794261
Lancet. 2018 Nov 10;392(10159):1789-1858
pubmed: 30496104
J Comp Neurol. 2011 Oct 15;519(15):3085-101
pubmed: 21618224
Cancer Res. 1984 Jan;44(1):112-9
pubmed: 6537799
Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20602-7
pubmed: 23185004
Best Pract Res Clin Rheumatol. 2017 Oct;31(5):676-687
pubmed: 30509413
Cell. 2017 Jul 27;170(3):470-482.e11
pubmed: 28735751
Drug Metab Dispos. 2002 Aug;30(8):869-74
pubmed: 12124303
J Control Release. 2016 Dec 28;244(Pt A):30-40
pubmed: 27836707
Science. 2019 Mar 22;363(6433):1303-1308
pubmed: 30765606
Int J Mol Sci. 2021 Mar 30;22(7):
pubmed: 33808364
Nature. 1986 Aug 28-Sep 3;322(6082):826-8
pubmed: 2427955
J Physiol. 2012 Jun 1;590(11):2577-89
pubmed: 22473783
PLoS One. 2016 Aug 24;11(8):e0161450
pubmed: 27556810
Angew Chem Int Ed Engl. 2021 Feb 8;60(6):3131-3137
pubmed: 33125829
Science. 2018 Oct 19;362(6412):
pubmed: 30190309
Science. 2001 Dec 14;294(5550):2372-5
pubmed: 11743207
Osteoarthritis Cartilage. 2019 Nov;27(11):1669-1679
pubmed: 31351964
Nature. 1996 Jan 18;379(6562):257-62
pubmed: 8538791
Nat Rev Drug Discov. 2015 Jul;14(7):475-86
pubmed: 26091267
Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8428-33
pubmed: 24850863
Science. 2019 Mar 22;363(6433):1309-1313
pubmed: 30765605
Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1527-32
pubmed: 9037087
Curr Pain Headache Rep. 2001 Jun;5(3):227-36
pubmed: 11309210
Arthritis Res Ther. 2021 Apr 7;23(1):103
pubmed: 33827672
BMJ. 2011 Jan 11;342:c7086
pubmed: 21224324
Nat Commun. 2017 Feb 16;8:14205
pubmed: 28205548
Science. 2018 Oct 19;362(6412):
pubmed: 30049784
Nat Commun. 2021 Jan 4;12(1):128
pubmed: 33397917

Auteurs

Megan M McCollum (MM)

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Megan Larmore (M)

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Shingo Ishihara (S)

Division of Rheumatology, Rush University Medical Center, Chicago, IL 60612, USA.

Leo C T Ng (LCT)

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Louise F Kimura (LF)

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Eduardo Guadarrama (E)

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

My C Ta (MC)

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Thuy N Vien (TN)

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Grant B Frost (GB)

Department of Chemistry, Northwestern University, Evanston, IL 60208, USA.

Karl A Scheidt (KA)

Department of Chemistry, Northwestern University, Evanston, IL 60208, USA.

Rachel E Miller (RE)

Division of Rheumatology, Rush University Medical Center, Chicago, IL 60612, USA.

Paul G DeCaen (PG)

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address: paul.decaen@northwestern.edu.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Potentiels de membrane › Potentiels d'action › Targeting the tamoxifen receptor within sodium...
questionsmedicales.fr › Système nerveux › Système nerveux périphérique › Nerfs périphériques › Nerfs spinaux › Racines des nerfs spinaux › Ganglions sensitifs des nerfs spinaux › Targeting the tamoxifen receptor within sodium...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Targeting the tamoxifen receptor within sodium...
questionsmedicales.fr › Cellules › Neurones › Neurones afférents › Cellules réceptrices sensorielles › Nocicepteurs › Targeting the tamoxifen receptor within sodium...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Sensation › Douleur › Targeting the tamoxifen receptor within sodium...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Composés benzylidéniques › Stilbènes › Tamoxifène › Targeting the tamoxifen receptor within sodium...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Canaux sodiques voltage-dépendants › Targeting the tamoxifen receptor within sodium...