Major complications after percutaneous biopsy of native or transplanted liver in pediatric patients: a nationwide inpatient database study in Japan.
Impatient database study
Major complications
Native liver
Pediatric percutaneous liver biopsy
Transplanted liver
Journal
BMC gastroenterology
ISSN: 1471-230X
Titre abrégé: BMC Gastroenterol
Pays: England
ID NLM: 100968547
Informations de publication
Date de publication:
24 Aug 2022
24 Aug 2022
Historique:
received:
25
05
2022
accepted:
03
08
2022
entrez:
24
8
2022
pubmed:
25
8
2022
medline:
27
8
2022
Statut:
epublish
Résumé
Although major complication rates following percutaneous liver biopsy (PLB) have been reported to be higher in children than in adults, scarce data are available regarding pediatric patients stratified by native and transplanted liver. We aimed to assess the factors associated with major complications after percutaneous biopsy of native or transplanted liver using a nationwide inpatient database. Using the Japanese Diagnosis Procedure Combination database, we retrospectively identified pediatric patients who underwent PLB between 2010 and 2018. We described major complication rates and analyzed factors associated with major complications following PLB, stratified by native and transplanted liver. We identified 3584 pediatric PLBs among 1732 patients from 239 hospitals throughout Japan during the study period, including 1310 in the native liver and 2274 in the transplanted liver. Major complications following PLB were observed in 0.5% (n = 18) of the total cases; PLB in the transplanted liver had major complications less frequently than those in the native liver (0.2% vs. 1.0%, p = 0.002). The occurrence of major complications was associated with younger age, liver cancers, unscheduled admission, anemia or coagulation disorders in cases with native liver, while it was associated with younger age alone in cases with transplanted liver. The present study, using a nationwide database, found that major complications occurred more frequently in pediatric cases with native liver and identified several factors associated with its major complications.
Identifiants
pubmed: 36002811
doi: 10.1186/s12876-022-02476-7
pii: 10.1186/s12876-022-02476-7
pmc: PMC9404589
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
395Subventions
Organisme : the Ministry of Health, Labour and Welfare, Japan
ID : 19AA2007 and 20AA2005
Organisme : the Ministry of Education, Culture, Sports, Science and Technology, Japan
ID : 20H03907
Informations de copyright
© 2022. The Author(s).
Références
AJR Am J Roentgenol. 2006 Dec;187(6):W644-9
pubmed: 17114519
Digestion. 2003;67(3):138-45
pubmed: 12853725
Diagn Interv Radiol. 2019 Jan;25(1):71-80
pubmed: 30644369
J Pediatr Gastroenterol Nutr. 2014 Jun;58(6):756-61
pubmed: 24509302
Pediatrics. 2010 Oct;126(4):647-55
pubmed: 20855394
J Pediatr Gastroenterol Nutr. 2013 Nov;57(5):644-8
pubmed: 23799457
AJR Am J Roentgenol. 2013 Sep;201(3):645-50
pubmed: 23971459
Pediatr Transplant. 2021 Jun;25(4):e13997
pubmed: 33704883
J Pediatr Gastroenterol Nutr. 2000 Nov;31(5):536-9
pubmed: 11144439
Am J Transplant. 2019 May;19(5):1545-1551
pubmed: 30614623
Am J Gastroenterol. 2020 May;115(5):786-789
pubmed: 31714363
Nutrients. 2021 Feb 07;13(2):
pubmed: 33562369
J Pediatr Gastroenterol Nutr. 2013 Nov;57(5):638-43
pubmed: 24177785
J Pediatr Gastroenterol Nutr. 2012 Jul;55(1):82-7
pubmed: 22249806
Pediatr Gastroenterol Hepatol Nutr. 2019 Jul;22(4):377-386
pubmed: 31338313
J Pediatr Gastroenterol Nutr. 2010 Nov;51(5):635-7
pubmed: 20890218
N Engl J Med. 2018 Oct 04;379(14):1303-1312
pubmed: 30281992
Int J Gen Med. 2021 Sep 11;14:5563-5571
pubmed: 34539186
BMC Pediatr. 2014 Aug 08;14:199
pubmed: 25102958
Clin Pediatr Endocrinol. 2011 Apr;20(2):47-9
pubmed: 23926394
Pediatr Radiol. 2009 Sep;39(9):959-61
pubmed: 19506846
J Clin Epidemiol. 2015 Sep;68(9):1028-35
pubmed: 25596112