Rare ectopic thyroid tissue as multiple bilateral pulmonary nodules: a case report and literature review.
Case report
Ectopic thyroid
Pulmonary nodules
VATS
Journal
Journal of cardiothoracic surgery
ISSN: 1749-8090
Titre abrégé: J Cardiothorac Surg
Pays: England
ID NLM: 101265113
Informations de publication
Date de publication:
24 Aug 2022
24 Aug 2022
Historique:
received:
19
03
2022
accepted:
18
08
2022
entrez:
24
8
2022
pubmed:
25
8
2022
medline:
27
8
2022
Statut:
epublish
Résumé
The prevalence of ectopic thyroid tissue is 1 in every 100,000 to 300,000 persons in the general population, and ectopic thyroid tissue in the bilateral lung lobes is even rarer. Due to its rarity, there is no definitive or standard guidance on the diagnosis and treatment of ectopic thyroid tissue presenting as multiple bilateral pulmonary nodules. A 56-year-old woman presented with multiple bilateral pulmonary nodules, and the patient had a history of hyperthyroidism but had no symptoms of ectopic thyroid tissue. Computed tomography (CT) demonstrated multiple solid nodules in both lungs, and the largest nodule (sized 15 × 14 mm) was located in segment 5 of the upper left lung. The initial diagnosis based on imaging was metastatic malignancies. Positron emission tomography-computed tomography (PET-CT) showed multiple bilateral intrapulmonary nodules that had slightly increased metabolism (SUVmax 1.7). The largest pulmonary nodule and another nodule in the left lung were resected by video-assisted thoracoscopy surgery (VATS). The pathological and immunohistochemical (IHC) examinations confirmed a diagnosis of ectopic thyroid tissue. No postoperative adjuvant therapy was given, and the patient was discharged 3 days after the operation and had regular follow-up examinations. The diagnosis of ectopic thyroid tissue in the bilateral lung lobes is extremely difficult and should be considered carefully. PET-CT and surgical resection of intrapulmonary nodules are alternatives for clinicians in diagnosing ectopic thyroid tissue. Regular postoperative follow-up is needed.
Sections du résumé
BACKGROUND
BACKGROUND
The prevalence of ectopic thyroid tissue is 1 in every 100,000 to 300,000 persons in the general population, and ectopic thyroid tissue in the bilateral lung lobes is even rarer. Due to its rarity, there is no definitive or standard guidance on the diagnosis and treatment of ectopic thyroid tissue presenting as multiple bilateral pulmonary nodules.
CASE PRESENTATION
METHODS
A 56-year-old woman presented with multiple bilateral pulmonary nodules, and the patient had a history of hyperthyroidism but had no symptoms of ectopic thyroid tissue. Computed tomography (CT) demonstrated multiple solid nodules in both lungs, and the largest nodule (sized 15 × 14 mm) was located in segment 5 of the upper left lung. The initial diagnosis based on imaging was metastatic malignancies. Positron emission tomography-computed tomography (PET-CT) showed multiple bilateral intrapulmonary nodules that had slightly increased metabolism (SUVmax 1.7). The largest pulmonary nodule and another nodule in the left lung were resected by video-assisted thoracoscopy surgery (VATS). The pathological and immunohistochemical (IHC) examinations confirmed a diagnosis of ectopic thyroid tissue. No postoperative adjuvant therapy was given, and the patient was discharged 3 days after the operation and had regular follow-up examinations.
CONCLUSION
CONCLUSIONS
The diagnosis of ectopic thyroid tissue in the bilateral lung lobes is extremely difficult and should be considered carefully. PET-CT and surgical resection of intrapulmonary nodules are alternatives for clinicians in diagnosing ectopic thyroid tissue. Regular postoperative follow-up is needed.
Identifiants
pubmed: 36002829
doi: 10.1186/s13019-022-01962-z
pii: 10.1186/s13019-022-01962-z
pmc: PMC9404587
doi:
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
205Subventions
Organisme : The Science and Technology Project of Bao'an
ID : NO.2021JD95
Organisme : The Science and Technology Project of Bao'an
ID : NO.2021JD95
Informations de copyright
© 2022. The Author(s).
Références
Orv Hetil. 2013 Jan 6;154(1):28-32
pubmed: 23274231
Clin Gastroenterol Hepatol. 2020 Dec;18(13):e157
pubmed: 31593772
Eur J Cardiothorac Surg. 2001 May;19(5):562-5
pubmed: 11343931
Acta Cytol. 2018;62(5-6):318-326
pubmed: 30380531
Diagn Pathol. 2015 Jun 06;10:61
pubmed: 26047938
J Thorac Dis. 2019 Feb;11(2):535-541
pubmed: 30962997
Diagn Interv Imaging. 2016 Mar;97(3):373-5
pubmed: 26493761
Gland Surg. 2020 Jun;9(3):806-811
pubmed: 32775272
Medicine (Baltimore). 2019 Aug;98(35):e16832
pubmed: 31464909
J Clin Endocrinol Metab. 2011 Sep;96(9):2684-91
pubmed: 21752893
QJM. 2019 Dec 1;112(12):927-928
pubmed: 31432085
Int J Surg. 2014;12 Suppl 1:S3-11
pubmed: 24887357
Medicine (Baltimore). 2019 Dec;98(50):e18293
pubmed: 31852107
Eur J Endocrinol. 2011 Sep;165(3):375-82
pubmed: 21715415
Dtsch Med Wochenschr. 2000 Apr 7;125(14):421-4
pubmed: 10812366
Thyroid. 2012 Jul;22(7):755-9
pubmed: 22650161
Gen Thorac Cardiovasc Surg. 2021 Mar;69(3):564-567
pubmed: 32939627
Arch Bronconeumol. 2002 Sep;38(9):415-20
pubmed: 12237012