Proton therapy in the treatment of hepatocellular carcinoma.
active scanning
hepatocellular carcinoma
photon therapy
proton therapy
review
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2022
2022
Historique:
received:
01
06
2022
accepted:
13
07
2022
entrez:
25
8
2022
pubmed:
26
8
2022
medline:
26
8
2022
Statut:
epublish
Résumé
Liver cancer represents one of the most common causes of death from cancer worldwide. Hepatocellular carcinoma (HCC) accounts for 90% of all primary liver cancers. Among local therapies, evidence regarding the use of radiation therapy is growing. Proton therapy currently represents the most advanced radiation therapy technique with unique physical properties which fit well with liver irradiation. Here, in this review, we aim to 1) illustrate the rationale for the use of proton therapy (PT) in the treatment of HCC, 2) discuss the technical challenges of advanced PT in this disease, 3) review the major clinical studies regarding the use of PT for HCC, and 4) analyze the potential developments and future directions of PT in this setting.
Identifiants
pubmed: 36003769
doi: 10.3389/fonc.2022.959552
pmc: PMC9393743
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
959552Informations de copyright
Copyright © 2022 Dionisi, Scartoni, Fracchiolla, Giacomelli, Siniscalchi, Goanta, Cianchetti, Sanguineti and Brolese.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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