Biomechanical engineering analysis of commonly utilized mitral neochordae.

3D, 3-dimensional ANOVA, analysis of variance MV, mitral valve PM, papillary muscle PTFE, polytetrafluoroethylene biomechanics mitral valve repair neochordae

Journal

JTCVS open
ISSN: 2666-2736
Titre abrégé: JTCVS Open
Pays: Netherlands
ID NLM: 101768541

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 09 07 2021
accepted: 14 07 2021
entrez: 25 8 2022
pubmed: 26 8 2022
medline: 26 8 2022
Statut: epublish

Résumé

To evaluate the suture rupture forces of commonly clinically utilized neochord repair techniques to identify the most biomechanically resistant most biomechanically resistant technique. Several types of neochord techniques (standard interrupted neochordae, continuous running neochordae, and loop technique), numbers of neochordae, and suture calibers (polytetrafluoroethylene CV-3 to CV-6) were compared. To perform the tests, both ends of the neochordae were loaded in a tensile force analysis machine. During the test, the machine applied tension to the neochord until rupture was achieved. The tests were performed 3 times for each variation, and the rupture forces were averaged for statistical analysis. Rupture force was significantly higher for running neochordae relative to interrupted neochordae ( Under experimental conditions, the running neochord technique has the best mechanical performance due to an increased rupture force. If using running neochordae, more than 1 independent set of multiple running neochordae are advised (ie, >2 independent sets of multiple running neochordae in each set).

Identifiants

pubmed: 36004068
doi: 10.1016/j.xjon.2021.07.040
pii: S2666-2736(21)00337-5
pmc: PMC9390398
doi:

Types de publication

Journal Article

Langues

eng

Pagination

263-275

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL089315
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL152155
Pays : United States

Informations de copyright

© 2021 The Author(s).

Références

Heart Fail Rev. 2006 Sep;11(3):241-57
pubmed: 17041764
J Heart Valve Dis. 2003 Mar;12(2):156-61
pubmed: 12701786
Ann Thorac Surg. 2022 Apr;113(4):1136-1143
pubmed: 34022210
Ann Thorac Surg. 2010 Apr;89(4):1163-70; discussion 1170
pubmed: 20338326
Ann Thorac Surg. 2000 Dec;70(6):2166-8
pubmed: 11156150
J Thorac Cardiovasc Surg. 2015 Nov;150(5):1303-12.e4
pubmed: 26277475
J Thorac Cardiovasc Surg. 2014 Jul;148(1):138-43
pubmed: 24041766
Multimed Man Cardiothorac Surg. 2019 Dec 19;2019:
pubmed: 31990155
J Biomech Eng. 2020 Jan 1;142(1):
pubmed: 31253992
J Card Surg. 1989 Dec;4(4):286-90
pubmed: 2520006
Eur Heart J. 2010 Aug;31(16):1958-66
pubmed: 20624767
Eur J Cardiothorac Surg. 2021 Jan 4;59(1):180-186
pubmed: 32776150
Med Eng Phys. 2019 Dec;74:121-128
pubmed: 31564499

Auteurs

Mateo Marin-Cuartas (M)

Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif.
University Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.

Annabel M Imbrie-Moore (AM)

Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif.
Department of Mechanical Engineering, Stanford University, Stanford, Calif.

Yuanjia Zhu (Y)

Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif.
Department of Bioengineering, Stanford University, Stanford, Calif.

Matthew H Park (MH)

Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif.
Department of Mechanical Engineering, Stanford University, Stanford, Calif.

Robert Wilkerson (R)

Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif.

Matthew Leipzig (M)

Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif.

Michael A Borger (MA)

University Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.

Y Joseph Woo (YJ)

Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif.
Department of Bioengineering, Stanford University, Stanford, Calif.

Classifications MeSH