Aortic valve endocarditis in patients with bicuspid and tricuspid aortic valves.

AI, aortic insufficiency AVR, aortic valve replacement BAV, bicuspid aortic valve HR, hazard ratio IE, infective endocarditis IQR, interquartile range IV, intravenous OR, odds ratio TAV, tricuspid aortic valve aortic valve aortic valve replacement bicuspid aortic valve endocarditis reoperation survival

Journal

JTCVS open
ISSN: 2666-2736
Titre abrégé: JTCVS Open
Pays: Netherlands
ID NLM: 101768541

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 02 09 2021
accepted: 03 09 2021
entrez: 25 8 2022
pubmed: 26 8 2022
medline: 26 8 2022
Statut: epublish

Résumé

To determine the long-term survival and rate of reoperation after surgical treatment of infective endocarditis (IE) in patients with a bicuspid aortic valve (BAV) and patients with a tricuspid aortic valve (TAV). Between 1997 and 2017, 210 patients underwent surgical treatment for native aortic valve endocarditis, including 51 patients with BAV (24%) and 159 patients with TAV (76%). Data were obtained from the Society of Thoracic Surgeons data warehouse and hospital medical record review, supplemented with surveys and national death index data for more complete follow-up. Compared with the TAV IE group, the BAV IE group was significantly younger (42 years vs 54 years) and had lower incidence rates of hypertension, coronary artery disease, and congestive heart failure (CHF). There were no significant between-group differences in postoperative stroke, sepsis, pacemaker requirement, or in-hospital mortality (2.0% vs 4.4%). Liver disease was a risk factor for operative mortality (odds ratio [OR], 13; 95% CI, 3.3-30; BAV patients develop IE requiring surgery at a younger age than TAV patients, but have significantly better long-term survival. Early detection of BAV is important to prevent IE and provide aggressive surgical treatment should IE occur.

Identifiants

pubmed: 36004079
doi: 10.1016/j.xjon.2021.09.007
pii: S2666-2736(21)00302-8
pmc: PMC9390515
doi:

Types de publication

Journal Article

Langues

eng

Pagination

228-236

Subventions

Organisme : NHLBI NIH HHS
ID : K08 HL130614
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL141891
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL151776
Pays : United States

Informations de copyright

© 2021 The Author(s).

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Auteurs

Tan Le (T)

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Nathan J Graham (NJ)

University of Michigan Medical School, Ann Arbor, Mich.

Aroma Naeem (A)

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Jeffrey Clemence (J)

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Juan Caceres (J)

University of Michigan Medical School, Ann Arbor, Mich.

Xiaoting Wu (X)

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Himanshu J Patel (HJ)

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Karen M Kim (KM)

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

G Michael Deeb (GM)

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Bo Yang (B)

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Classifications MeSH