Blood-brain barrier (BBB)-on-a-chip: a promising breakthrough in brain disease research.

Biological Transport Blood-Brain Barrier Brain Brain Neoplasms / pathology Humans Lab-On-A-Chip Devices Tumor Microenvironment

Journal

Lab on a chip
ISSN: 1473-0189
Titre abrégé: Lab Chip
Pays: England
ID NLM: 101128948

Informations de publication

Date de publication:
27 09 2022
Historique:
pubmed: 26 8 2022
medline: 30 9 2022
entrez: 25 8 2022
Statut: epublish

Résumé

The blood-brain barrier (BBB) represents a key challenge in developing brain-penetrating therapeutic molecules. BBB dysfunction is also associated with the onset and progression of various brain diseases. The BBB-on-a-chip (μBBB), an organ-on-chip technology, has emerged as a powerful

Identifiants

DOI: 10.1039/d2lc00305h PMID: 36004771
pubmed: 36004771
doi: 10.1039/d2lc00305h
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3579-3602

Auteurs

Bo Peng (B)

Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an 710072, China. iamlli@nwpu.edu.cn.
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia. nicolas.voelcker@monash.edu.
ORCID: 0000-0002-7626-8455

Shiping Hao (S)

Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an 710072, China. iamlli@nwpu.edu.cn.

Ziqiu Tong (Z)

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia. nicolas.voelcker@monash.edu.

Hua Bai (H)

Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an 710072, China. iamlli@nwpu.edu.cn.

Sijun Pan (S)

The Institute of Flexible Electronics (IFE, Future Technologies), Xiamen University, Xiamen 361005, Fujian, China.

Kah-Leong Lim (KL)

Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, 308232, Singapore.

Lin Li (L)

Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an 710072, China. iamlli@nwpu.edu.cn.
Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), Nanjing 211800, China.
The Institute of Flexible Electronics (IFE, Future Technologies), Xiamen University, Xiamen 361005, Fujian, China.

Nicolas H Voelcker (NH)

Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an 710072, China. iamlli@nwpu.edu.cn.
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia. nicolas.voelcker@monash.edu.
ORCID: 0000-0002-1536-7804

Wei Huang (W)

Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an 710072, China. iamlli@nwpu.edu.cn.
Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), Nanjing 211800, China.
The Institute of Flexible Electronics (IFE, Future Technologies), Xiamen University, Xiamen 361005, Fujian, China.

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Transport biologique › Blood-brain barrier (BBB)-on-a-chip: a...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Barrière hémato-encéphalique › Blood-brain barrier (BBB)-on-a-chip: a...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Blood-brain barrier (BBB)-on-a-chip: a...
questionsmedicales.fr › Maladies du système nerveux › Tumeurs du système nerveux › Tumeurs du système nerveux central › Tumeurs du cerveau › Blood-brain barrier (BBB)-on-a-chip: a...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Blood-brain barrier (BBB)-on-a-chip: a...
questionsmedicales.fr › Équipement et fournitures › Équipement et fournitures électriques › Laboratoires sur puces › Blood-brain barrier (BBB)-on-a-chip: a...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Microenvironnement cellulaire › Microenvironnement tumoral › Blood-brain barrier (BBB)-on-a-chip: a...