Dextrin-Based Nanohydrogels for Rokitamycin Prolonged Topical Delivery.
cyclodextrin
formulation
linecaps
nanohydrogels
nanosponges
rokitamycin
Journal
Gels (Basel, Switzerland)
ISSN: 2310-2861
Titre abrégé: Gels
Pays: Switzerland
ID NLM: 101696925
Informations de publication
Date de publication:
08 Aug 2022
08 Aug 2022
Historique:
received:
13
06
2022
revised:
01
08
2022
accepted:
02
08
2022
entrez:
25
8
2022
pubmed:
26
8
2022
medline:
26
8
2022
Statut:
epublish
Résumé
Macrolides are widely used antibiotics with a broad spectrum of activity. The development of drug carriers to deliver this type of antibiotics has attracted much research. The present study aims at developing new swellable dextrin-based nanohydrogels for the topical delivery of rokitamycin, as model macrolide. Rokitamycin is a synthetic analogous of macrolides with advantageous characteristics as far as bacterial uptake and post-antibiotic effect are concerned. It is also indicated for the treatment of severe infections caused by
Identifiants
pubmed: 36005092
pii: gels8080490
doi: 10.3390/gels8080490
pmc: PMC9407297
pii:
doi:
Types de publication
Journal Article
Langues
eng
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