Discovery of Ircinianin Lactones B and C-Two New Cyclic Sesterterpenes from the Marine Sponge

Ircinia wistarii Leishmania donovani NCI-60 Plasmodium falciparum antiprotozoal activity bioactivity screening ircinianin-derivates sesterterpene sponge

Journal

Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729

Informations de publication

Date de publication:
19 Aug 2022
Historique:
received: 14 06 2022
revised: 13 08 2022
accepted: 17 08 2022
entrez: 25 8 2022
pubmed: 26 8 2022
medline: 27 8 2022
Statut: epublish

Résumé

Two new ircinianin-type sesterterpenoids, ircinianin lactone B and ircinianin lactone C (

Identifiants

pubmed: 36005535
pii: md20080532
doi: 10.3390/md20080532
pmc: PMC9410537
pii:
doi:

Substances chimiques

Lactones 0
Sesterterpenes 0
Terpenes 0
ircinianin 63555-48-6

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Cluster of Excellence ´Controlling microbes to fight infection´
ID : 390838134

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Auteurs

Thomas Majer (T)

Department of Pharmaceutical Biology, Pharmaceutical Institute, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.

Keshab Bhattarai (K)

Department of Pharmaceutical Biology, Pharmaceutical Institute, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.

Jan Straetener (J)

Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine (IMIT), University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany.

Justus Pohlmann (J)

Institute for Medical Virology and Epidemiology, Section Molecular Virology, University Hospital Tübingen, 72076 Tübingen, Germany.

Patrick Cahill (P)

Cawthron Institute, 98 Halifax Street East, Nelson 7010, New Zealand.

Markus O Zimmermann (MO)

Lab for Molecular Design and Pharmaceutical Biophysics, Department of Pharmacy and Biochemistry, Institute of Pharmaceutical Sciences, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.

Marc P Hübner (MP)

Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, 53127 Bonn, Germany.
German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany.

Marcel Kaiser (M)

Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland.
Faculty of Science, University of Basel, Petersplatz 1, 4002 Basel, Switzerland.

Johan Svenson (J)

Cawthron Institute, 98 Halifax Street East, Nelson 7010, New Zealand.

Michael Schindler (M)

Institute for Medical Virology and Epidemiology, Section Molecular Virology, University Hospital Tübingen, 72076 Tübingen, Germany.

Heike Brötz-Oesterhelt (H)

Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine (IMIT), University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany.
Cluster of Excellence 'Controlling Microbes to Fight Infections', University of Tübingen, 72076 Tübingen, Germany.
German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.

Frank M Boeckler (FM)

Lab for Molecular Design and Pharmaceutical Biophysics, Department of Pharmacy and Biochemistry, Institute of Pharmaceutical Sciences, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Interfaculty Institute for Biomedical Informatics (IBMI), University of Tübingen, Sand 14, 72076 Tübingen, Germany.

Harald Gross (H)

Department of Pharmaceutical Biology, Pharmaceutical Institute, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Cluster of Excellence 'Controlling Microbes to Fight Infections', University of Tübingen, 72076 Tübingen, Germany.
German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.

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Classifications MeSH