A cognitive process occurring during sleep is revealed by rapid eye movements.
Journal
Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511
Informations de publication
Date de publication:
26 08 2022
26 08 2022
Historique:
entrez:
25
8
2022
pubmed:
26
8
2022
medline:
30
8
2022
Statut:
ppublish
Résumé
Since the discovery of rapid eye movement (REM) sleep, the nature of the eye movements that characterize this sleep phase has remained elusive. Do they reveal gaze shifts in the virtual environment of dreams or simply reflect random brainstem activity? We harnessed the head direction (HD) system of the mouse thalamus, a neuronal population whose activity reports, in awake mice, their actual HD as they explore their environment and, in sleeping mice, their virtual HD. We discovered that the direction and amplitude of rapid eye movements during REM sleep reveal the direction and amplitude of the ongoing changes in virtual HD. Thus, rapid eye movements disclose gaze shifts in the virtual world of REM sleep, thereby providing a window into the cognitive processes of the sleeping brain.
Identifiants
pubmed: 36007021
doi: 10.1126/science.abp8852
pmc: PMC9933572
mid: NIHMS1849803
doi:
Banques de données
Dryad
['10.7272/Q6P26WDC']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
999-1004Subventions
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY025668
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS123912
Pays : United States
Organisme : NINDS NIH HHS
ID : U19 NS107613
Pays : United States
Commentaires et corrections
Type : CommentIn
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