Glycemic control and antioxidant potential of distinct fractions of camelus dromedaries fresh milk in streptozocin induced diabetic rats.
Journal
Pakistan journal of pharmaceutical sciences
ISSN: 1011-601X
Titre abrégé: Pak J Pharm Sci
Pays: Pakistan
ID NLM: 9426356
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
entrez:
26
8
2022
pubmed:
27
8
2022
medline:
30
8
2022
Statut:
ppublish
Résumé
To analyze the antiglycemic effects and to evaluate the anti-oxidant levels in pre and post-camel milk fractions treated albino diabetic rats, sixty male Swiss albino rats weighing 30-40gm aged 2 to 3 months were randomly divided into six groups, A, B, C, D, E & F, each comprised of 10 animals. as Group A: Normal control, Group B: Streptozocin induced Diabetic group while Groups C, D, E & F were diabetic groups treated with various fractions of camel milk. Noteworthy alteration in blood glucose and antioxidant activity was observed between disease control (group B) and all the treated groups with a percentage decrease of about 25%, 12.98%, 11.57% and 10.17% in blood sugar in groups C, D, E and F respectively. Changes in total antioxidant capacity were significant with the rise of 92.30%, 30.76%, 46.15% and 38.46% respectively in groups C, D, E and F. Percentage difference in superoxide dismutase between group B and Group C of 85% was highest as compared to 45.90 %, 52.45% and 39.34% for groups D, E and F. Group C also showed a significantly higher increase in serum copper, zinc and Vitamin C. It is inferred that Camel milk has significant antiglycemic and antioxidant potential and may prove good complementary therapeutics for diabetes.
Substances chimiques
Antioxidants
0
Blood Glucose
0
Streptozocin
5W494URQ81
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM