CAG Repeat Instability in the Peripheral and Central Nervous System of Transgenic Huntington's Disease Monkeys.
Huntington’s disease
central nervous system
peripheral system
transgenic monkey model
trinucleotide repeats
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
02 Aug 2022
02 Aug 2022
Historique:
received:
15
06
2022
revised:
16
07
2022
accepted:
22
07
2022
entrez:
26
8
2022
pubmed:
27
8
2022
medline:
27
8
2022
Statut:
epublish
Résumé
Huntington's Disease (HD) is an autosomal dominant disease that results in severe neurodegeneration with no cure. HD is caused by the expanded CAG trinucleotide repeat (TNR) on the Huntingtin gene (
Identifiants
pubmed: 36009409
pii: biomedicines10081863
doi: 10.3390/biomedicines10081863
pmc: PMC9405741
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NIH HHS
ID : P51 OD011132
Pays : United States
Organisme : National Institute of Health
ID : P51OD11132
Organisme : National Institute of Health
ID : OD010930
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