Generation and Characterization of Novel iPSC Lines from a Portuguese Family Bearing Heterozygous and Homozygous

GRN mutations Portuguese family frontotemporal lobar degeneration human-induced pluripotent stem cells reprograming

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
06 Aug 2022
Historique:
received: 06 07 2022
revised: 02 08 2022
accepted: 04 08 2022
entrez: 26 8 2022
pubmed: 27 8 2022
medline: 27 8 2022
Statut: epublish

Résumé

Mutations in granulin (

Identifiants

pubmed: 36009452
pii: biomedicines10081905
doi: 10.3390/biomedicines10081905
pmc: PMC9405606
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Takeda (Japan)
ID : COCKPI-T Program
Organisme : Fundação para a Ciência e Tecnologia
ID : PTDC/MEC-NEU/4814/2020
Organisme : Fundação para a Ciência e Tecnologia
ID : CENTRO-01-0145-FEDER-000008 (BrainHealth2020)

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Auteurs

Ana Rafaela Oliveira (AR)

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
MIT-Portugal Ph.D. Program, NOVA School of Science and Technology, New University of Lisbon, 2829-516 Caparica, Portugal.

Solange Martins (S)

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.

Giuseppe Cammarata (G)

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789 Coimbra, Portugal.
Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.

Mariana Martins (M)

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.

Ana Maria Cardoso (AM)

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789 Coimbra, Portugal.

Maria Rosário Almeida (MR)

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.

Maria do Carmo Macário (M)

Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Neurology Department, Centro Hospitalar e Universitário de Coimbra, 3004-531 Coimbra, Portugal.
Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.

Isabel Santana (I)

Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Neurology Department, Centro Hospitalar e Universitário de Coimbra, 3004-531 Coimbra, Portugal.
Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.

João Peça (J)

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Department of Life Sciences, Faculty of Science and Technology, University of Coimbra, 3000-456 Coimbra, Portugal.

Ana Luísa Cardoso (AL)

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789 Coimbra, Portugal.

Classifications MeSH