Putative Complementary Compounds to Counteract Insulin-Resistance in PCOS Patients.
L-arginine
N-acetyl cysteine
PCOS
antioxidants
carnitines
inositols
insulin resistance
lipoic acid
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
09 Aug 2022
09 Aug 2022
Historique:
received:
05
07
2022
revised:
25
07
2022
accepted:
04
08
2022
entrez:
26
8
2022
pubmed:
27
8
2022
medline:
27
8
2022
Statut:
epublish
Résumé
Polycystic ovary syndrome (PCOS) is the most frequent endocrine-metabolic disorder among women at reproductive age. The diagnosis is based on the presence of at least two out of three criteria of the Rotterdam criteria (2003). In the last decades, the dysmetabolic aspect of insulin resistance and compensatory hyperinsulinemia have been taken into account as the additional key features in the etiopathology of PCOS, and they have been widely studied. Since PCOS is a complex and multifactorial syndrome with different clinical manifestations, it is difficult to find the gold standard treatment. Therefore, a great variety of integrative treatments have been reported to counteract insulin resistance. PCOS patients need a tailored therapeutic strategy, according to the patient's BMI, the presence or absence of familiar predisposition to diabetes, and the patient's desire to achieve pregnancy or not. The present review analyzes and discloses the main clinical insight of such complementary substances.
Identifiants
pubmed: 36009471
pii: biomedicines10081924
doi: 10.3390/biomedicines10081924
pmc: PMC9406066
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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